DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment puc and Dusp12

DIOPT Version :9

Sequence 1:	NP_524273.1	Gene:	puc / 40958	FlyBaseID:	FBgn0243512	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_075662.2	Gene:	Dusp12 / 80915	MGIID:	1890614	Length:	339	Species:	Mus musculus

Alignment Length:	297	Identity:	75/297 - (25%)
Similarity:	117/297 - (39%)	Gaps:	52/297 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 NGGGRTPALTRSCSSPAVYDIETHPASPVFPHLLLGNGRDADDPS---SVGANCVLNVTCQS--P 168
            |.|....|.|.|.:|.|.:.:|..|.      |.||......:|.   ..|...||.|..:.  |
Mouse     8 NHGCERQAPTASPASSAGHAVEVRPG------LYLGGAAAVAEPGHLREAGITAVLTVDSEPAFP 66

  Fly   169 NESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMR 233
            ..:..:||:.:.:||.|.|..::..:......||..||..|..||:|||||:|||..:.:|::|:
Mouse    67 AGAGFEGLRSLFVPALDKPETDLLSHLDRCVAFIGQARSEGRAVLVHCHAGVSRSVAVVMAFIMK 131

  Fly   234 YKSLSLLEAYKLVKVARPIISPNLNF---------MGQLLELEQNLRKSGVLAPAT---PHL-NS 285
            ...|:..:||.:::..:|....|..|         ||..::......|...|...|   |.| |.
Mouse   132 TDQLTFEKAYDILRTVKPEAKVNEGFEWQLKLYEAMGYEVDTSSAFYKQYRLQKVTEKCPKLWNL 196

  Fly   286 PS-----NPSSSSVGLSTQSSQLVEQPEEEEKREQRERGKSKSDSEAMDEDGFDYDDVDSGSGSL 345
            |.     :|::.|.||.........:......|.....|.|:                  |||.:
Mouse   197 PQELFAVDPTTISQGLKDDILYKCRKCRRSLFRHSSILGHSE------------------GSGPI 243

  Fly   346 AGSNCSSRLTSPP--ITPDDEAPSTSAAASSVSELDS 380
            |.::   :.|:|.  :|...:|..||.....|..::|
Mouse   244 AFAH---KRTAPSSVLTTGSQAQCTSYFIEPVQWMES 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	DSPc	133..267	CDD:238073	41/147 (28%)
puc	NP_524273.1	CDC14	<193..272	CDD:225297	25/87 (29%)
Dusp12	NP_075662.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25		6/16 (38%)
		DSPc	26..165	CDD:238073	40/144 (28%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q9UNI6	115..120		3/4 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810