Protein Alignment puc and DUSP16

DIOPT Version :9

• Sequence 1: NP_524273.1
• Gene: puc / 40958
• FlyBaseID: FBgn0243512
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_085143.1
• Gene: DUSP16 / 80824
• HGNCID: 17909
• Length: 665
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 137/539 - (25%)
• Similarity: 219/539 - (40%)
• Gaps: 151/539 - (28%)

  Fly    43 SVSHI--------QSEMKMRIKREAPCLLLFMPIQNTNNNN-RIGANQKDYPNKRSRENLA---- 94
            :.|||        ...||.|::::.  :|:...||::..:. .|..:||.....:|.:::|
Human    38 NTSHILEAININCSKLMKRRLQQDK--VLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSS 100

  Fly    95 -C------DEVTSTTSSSTAMNGG-------------GRTPALTRSCSSPAVYDIETHPASPVFP 139
             |      .::..:.:|...:.||             |:: .|..:|.|.....:.....:.:.|
Human   101 DCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKS-TLVPTCISQPCLPVANIGPTRILP 164

  Fly   140 HLLLGNGRDADDPSSV---GANCVLNV--TCQSPN---ESHLQGLKYMQIPASDTPHQNIKQYFQ 196
            :|.||..||..:...:   |...|||.  ||..|:   |||     ::::|.:|:..:.|..:..
Human   165 NLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH-----FLRVPVNDSFCEKILPWLD 224

  Fly   197 EAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMG 261
            ::.||||.|:.:...||:||.|||||||||||||:|:...:||.|||:.||..||.||||.||:|
Human   225 KSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLG 289

  Fly   262 QLLELEQNLR-KSGVLAPATP----HLNSPSNP-----------------------SSSSVGL-- 296
            |||:.|:.:: ::|...|.:.    ||..|:.|                       :|.:.|.
Human   290 QLLDYEKKIKNQTGASGPKSKLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRP 354

  Fly   297 ----------STQSSQLVEQP------------EEEEKREQRERG-----KSKSDSEAM------ 328
                      |.|.|.|.:.|            :..|...:.:|.     ||.|.|.:|
Human   355 VHPASVPSVPSVQPSLLEDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHG 419

  Fly   329 ---DEDGFDYDDVDSGSGSLAGSN--CSSRLTSPPITPDDEAPSTS---AAASSVSELDSPSSTS 385
               .||..:|   ...|.:|.|:|  |.   .||.....::.|.||   ..||...:|.:...:.
Human   420 FSSSEDALEY---YKPSTTLDGTNKLCQ---FSPVQELSEQTPETSPDKEEASIPKKLQTARPSD 478

  Fly   386 SSSGICSLLQSTSSSVSPRAISKPNLLSPTRQLALFKRNSPAKLRLDLESS-------------- 436
            |.|.....::::||..:.|     :||||..:....:.|........|.:|
Human   479 SQSKRLHSVRTSSSGTAQR-----SLLSPLHRSGSVEDNYHTSFLFGLSTSQQHLTKSAGLGLKG 538

  Fly   437 -----YAPASPIPN-TMPW 449
                 .||.:..|: |..|
Human   539 WHSDILAPQTSTPSLTSSW 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	DSPc	133..267	CDD:238073	61/141 (43%)
		CDC14	<193..272	CDD:225297	43/79 (54%)
DUSP16	NP_085143.1	DSP_MapKP	10..136	CDD:238723	18/99 (18%)
		DSPc	158..295	CDD:238073	61/141 (43%)
		CDC14	<207..300	CDD:225297	46/92 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..368		4/46 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	449..505		15/60 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	597..665

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4833
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.900