Protein Alignment puc and Dusp10

DIOPT Version :10

• Sequence 1: NP_524273.1
• Gene: puc / 40958
• FlyBaseID: FBgn0243512
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_071302.2
• Gene: Dusp10 / 63953
• MGIID: 1927070
• Length: 483
• Species: Mus musculus
• Alignment Length: 390
• Identity: 116/390 - (29%)
• Similarity: 171/390 - (43%)
• Gaps: 117/390 - (30%)

  Fly     6 ETQSSSNNNSNNTTTATSTAR--------NNNSHNGR--CECDGDGDSVSHIQSEM--------- 51
            :||:.:   :...|||..|:.        |||.:.|.  ....|.|..||....::
Mouse    93 QTQAIA---AGTATTAIGTSTTCPANQMVNNNENTGSVLSPSGGVGSPVSGTPKQLASIKIIYPN 154

  Fly    52 ----------KMRIKREAPCLLLFMPIQNTNNNNRIGA---NQKDYPNKR--------------- 88
                      |..:..:.|.::...|....|.::..||   |..|..::|
Mouse   155 DLAKKMTKCSKSHLPSQGPVIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISC 219

  Fly    89 -----------SRENLACDEVTSTTS-----------------------------SSTAMN---- 109
                       |:|.:..||.|:..|                             ||...|
Mouse   220 REGKDSFKRIFSKEIIVYDENTNEPSRVTPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHGNL 284

  Fly   110 -------------GGGRTPALTRSCSS-PAVYDIETHPASPVFPHLLLGNGRDADDPSS---VGA 157
                         |||.:.|.:....| |...|||....:|:.|.|.|||.:||.|..:   :..
Mouse   285 CDNSLQLQECREVGGGASAASSMLPQSVPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNI 349

  Fly   158 NCVLNVTCQSPNESHLQGL-KYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGIS 221
            ..|:|||...|...:.:|| .|.::||:|:..||::|||:||::|||:|.:.|..:|:||.||:|
Mouse   350 GYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVS 414

  Fly   222 RSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSGVLAPATPHLNSP 286
            |||||.|||:|::..:::.:|||.||..||||||||||||||||.|::| .:||    ||.:.:|
Mouse   415 RSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL-NNGV----TPRILTP 474

  Fly   287  286
            Mouse   475  474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	PTP_DSP_cys	135..281	CDD:475123	72/149 (48%)
Dusp10	NP_071302.2	DSP_MapKP	150..285	CDD:238723	18/134 (13%)
		Interaction with MAP kinases. /evidence=ECO:0000250	200..216		1/15 (7%)
		DSP_DUSP10	323..474	CDD:350415	74/155 (48%)