Protein Alignment puc and SSH1

DIOPT Version :9

• Sequence 1: NP_524273.1
• Gene: puc / 40958
• FlyBaseID: FBgn0243512
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_011536799.1
• Gene: SSH1 / 54434
• HGNCID: 30579
• Length: 1060
• Species: Homo sapiens
• Alignment Length: 683
• Identity: 134/683 - (19%)
• Similarity: 205/683 - (30%)
• Gaps: 264/683 - (38%)

  Fly    21 ATSTARNNNSHNG-----------RC-----ECDGDGDSVSHIQSEMKMRIKREAPCLLLFMPIQ 69
            |...||.:|...|           .|     .|..:.:::..::|     .:.::|.|.:..|.:
Human   199 ACEVARRHNYFPGGVALIWATYYESCISSEQSCINEWNAMQDLES-----TRPDSPALFVDKPTE 258

  Fly    70 NTNNNNRIGANQKDYPNKRSRENLACDEVTSTTSSSTAMNGGGRTPALTRSCSSPAVYDI----- 129
            .......|.|..:.....:..||:...|:.:.....  ||           |:...:.:.
Human   259 GERTERLIKAKLRSIMMSQDLENVTSKEIRNELEKQ--MN-----------CNLKELKEFIDNEM 310

  Fly   130 -----ETHPASPVFPHLLLG---NGRDADDPSSVGANCVLNVTCQSPNESHLQGL-KYMQIPASD 185
                 :....|.:|.||.||   |..:.::....|.:.:||||.:..|  ...|| .|..|...|
Human   311 LLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDN--FFPGLFAYHNIRVYD 373

  Fly   186 TPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVAR 250
            ....::..::.|||.||..|::..|:.|:||..|:||||:..|||.|:.....|.:||..||..|
Human   374 EETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKR 438

  Fly   251 PIISPNLNFMGQLLELEQNLRKS--------------------------GVLAPATPH------- 282
            .|..||..||.||.|.|..|..|                          |...|.||.
Human   439 SITRPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTPESQL 503

  Fly   283 --------------------------LNSPSNPSSSSVGLS------------------------ 297
                                      |.||.:.:.|.|.|.
Human   504 PFLDDAAQPGLGPPLPCCFRRLSDPLLPSPEDETGSLVHLEDPEREALLEEAAPPAEVHRPARQP 568

  Fly   298 TQSSQLVE--------------------QPEEEEKREQRERGK---------------------- 320
            .|.|.|.|                    |.||.|:.|....|:
Human   569 QQGSGLCEKDVKKKLEFGSPKGRSGSLLQVEETEREEGLGAGRWGQLPTQLDQNLLNSENLNNNS 633

  Fly   321 SKSDSEAMDEDGF---------DYDD-------VDSGSGSLAGSNCSS--------------RLT 355
            .:|....|::|..         .|..       ..||:...:...|..              .:|
Human   634 KRSCPNGMEDDAIFGILNKVKPSYKSCADCMYPTASGAPEASRERCEDPNAPAICTQPAFLPHIT 698

  Fly   356 SPPIT---------------PDDEAPSTSAAASSVSELDSPSSTSSSSGICSLLQSTSSSVSPRA 405
            |.|:.               |.:..|....|.|..::...|.:.::.....|||:  .|..:|:.
Human   699 SSPVAHLASRSRVPEKPASGPTEPPPFLPPAGSRRADTSGPGAGAALEPPASLLE--PSRETPKV 761

  Fly   406 ISKPNLLS--------PTRQLALFKRNSP---AKLRLDLESSYAPASPIPNTMPWL--------- 450
            :.|..||.        |:.::.:.:.:||   .|...||...::..|..|.|..:|
Human   762 LPKSLLLKNSHCDKNPPSTEVVIKEESSPKKDMKPAKDLRLLFSNESEKPTTNSYLMQHQESIIQ 826

  Fly   451 ------------------SVPSTPVCEEAPDSR 465
                              |||:.|    ||.||
Human   827 LQKAGLVRKHTKELERLKSVPADP----APPSR 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	DSPc	133..267	CDD:238073	51/137 (37%)
		CDC14	<193..272	CDD:225297	35/78 (45%)
SSH1	XP_011536799.1	SSH-N	41..248	CDD:212166	8/53 (15%)
		DEK_C	263..314	CDD:285919	8/63 (13%)
		DSPc	319..455	CDD:238073	51/137 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820