DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment puc and DUSP29

DIOPT Version :9

Sequence 1:	NP_524273.1	Gene:	puc / 40958	FlyBaseID:	FBgn0243512	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001003892.1	Gene:	DUSP29 / 338599	HGNCID:	23481	Length:	220	Species:	Homo sapiens

Alignment Length:	230	Identity:	60/230 - (26%)
Similarity:	98/230 - (42%)	Gaps:	67/230 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 SPAVYDIE----------THPASPVFPHLLLGNGRDADDP---SSVGANCVLNV------TCQSP 168
            :|..:::|          || .:.|:|.|.:|:...|.|.   ...|...|||.      ....|
Human    35 TPGAFELERLFWKGSPQYTH-VNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGP 98

  Fly   169 NESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTG-SRVLLHCHAGISRSATIAIAYVM 232
            :......::|..:.|.|.|..::..:|..|..||:.|.... |::|:||..|.|||||:.:||:|
Human    99 DYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLM 163

  Fly   233 RYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSGVLAPATPHLNSPSNPSSSSVGLS 297
            .:|.::|::|.:.|...|.:: ||..|:.||.||::
Human   164 IHKDMTLVDAIQQVAKNRCVL-PNRGFLKQLRELDK----------------------------- 198

  Fly   298 TQSSQLVEQPEEEEKREQRERGKSKSDSEAMDEDG 332
                |||:|    .:|.||:.|:        :|||
Human   199 ----QLVQQ----RRRSQRQDGE--------EEDG 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	DSPc	133..267	CDD:238073	44/143 (31%)
puc	NP_524273.1	CDC14	<193..272	CDD:225297	30/79 (38%)
DUSP29	NP_001003892.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29
		DUPD1	45..201	CDD:350423	48/190 (25%)
		Substrate binding. /evidence=ECO:0000305	146..153		3/6 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820