DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment puc and Dusp16

DIOPT Version :9

Sequence 1:	NP_524273.1	Gene:	puc / 40958	FlyBaseID:	FBgn0243512	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001100094.1	Gene:	Dusp16 / 297682	RGDID:	1310721	Length:	661	Species:	Rattus norvegicus

Alignment Length:	495	Identity:	134/495 - (27%)
Similarity:	207/495 - (41%)	Gaps:	114/495 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SVSHI--------QSEMKMRIKREAPCLLLFMPIQNTNNNN-RIGANQKDYPNKRSRE---NLAC 95
            :.|||        ...||.|::::.  :|:...||::..:. .|..:||.....:|.:   :|:.
  Rat    38 NTSHILEAININCSKLMKRRLQQDK--VLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVGSLSS 100

  Fly    96 D--------EVTSTTSSSTAMNGG-------------GRTPALTRSCSSPAVYDIETHPASPVFP 139
            |        ::..:.:|...:.||             |::..:....|.|.:....|.| :.:.|
  Rat   101 DCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCFPGLCEGKSTLVPTCISQPCLPVANTGP-TRILP 164

  Fly   140 HLLLGNGRDADDPSSV---GANCVLNV--TCQSPN---ESHLQGLKYMQIPASDTPHQNIKQYFQ 196
            :|.||..||..:...:   |...|||.  ||..|:   |||     ::::|.:|:..:.|..:..
  Rat   165 NLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESH-----FLRVPVNDSFCEKILPWLD 224

  Fly   197 EAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMG 261
            ::.||||.|:.:...||:||.|||||||||||||:|:...:||.|||:.||..||.||||.||||
  Rat   225 KSVDFIEKAKASNGCVLIHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFMG 289

  Fly   262 QLLELEQNL-RKSGVLAPATP----HLNSPSNP----------------------SSSSVGL--- 296
            ||::.|:.: .::|:..|.:.    ||:..|.|                      :|.:||.
  Rat   290 QLMDYEKTISSQTGMSGPKSKLKLLHLDKASEPVPAASEGGRKNALSLSPPCANSTSEAVGQRLV 354

  Fly   297 ------STQSSQLVEQP---------EEEEKREQRERGK----------SKSDSEAMDEDGFDYD 336
                  |.|.|.|.:.|         ...||.|...|.|          |.|.|.|....||..:
  Rat   355 HPASVPSLQPSLLEDSPLVQALSGLQLSSEKLEDSNRLKRSFSLDIKSVSYSASVAASLHGFSSE 419

  Fly   337 DV---DSGSGSLAGSNCSSRLT--SPPITPDDEAPSTSAAASSVSELDSPSSTSSSSGICSLLQS 396
            |.   ...|.:|.|   :|:|.  ||.....::.|.||...........|.:|..|....:.|.|
  Rat   420 DAMEYYKPSATLDG---TSKLCQFSPVQEVSEQTPETSPDKEEAHIPRQPQATRPSESQTTRLHS 481

  Fly   397 TSSSVSPRAISKPNLLSPTRQLALFKRNSPAKLRLDLESS 436
            ..:| |..:..:| ..||..:....:.|........|.:|
  Rat   482 VRTS-STGSTQRP-FFSPLHRSGSVEDNYHTNFLFGLSTS 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	DSPc	133..267	CDD:238073	62/141 (44%)
puc	NP_524273.1	CDC14	<193..272	CDD:225297	43/79 (54%)
Dusp16	NP_001100094.1	DSP_MapKP	10..136	CDD:238723	18/99 (18%)
Dusp16	NP_001100094.1	PTP_DSP_cys	158..301	CDD:421693	63/148 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I4680
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.870