DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment puc and Dusp27

DIOPT Version :9

Sequence 1:	NP_524273.1	Gene:	puc / 40958	FlyBaseID:	FBgn0243512	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	NP_001028516.2	Gene:	Dusp27 / 240892	MGIID:	2685055	Length:	1138	Species:	Mus musculus

Alignment Length:	387	Identity:	89/387 - (22%)
Similarity:	159/387 - (41%)	Gaps:	102/387 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 SSPAVYDIE-----------THPASPVFPHLLLGNGRDADDP---SSVGANCVLNVTCQSPNESH 172
            ::|.|.|::           .:....|:|::.:.....|.:.   ..:|...:||.       :|
Mouse   111 NTPCVLDLQRALTQDRQEAPRNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNA-------AH 168

  Fly   173 LQG------------LKYMQIPASDTPHQNIKQYFQEAYDFIEDARKT-GSRVLLHCHAGISRSA 224
            ..|            ::|:.:...|.|..:|.|:|::|.:|:::|..| ..:||:....||||||
Mouse   169 GTGVYTGSEFYTGLEIQYLGVEVDDFPEVDISQHFRKAAEFLDEALLTYRGKVLVSSEMGISRSA 233

  Fly   225 TIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNL------------------- 270
            .:.:||:|.:.|:::|||...|:..|.|. ||..|:.||.||.:.|
Mouse   234 VLVVAYLMIFHSMAILEALMTVRRKRAIY-PNDGFLKQLRELNEKLMEEREEEDGEEESEEDAGS 297

  Fly   271 ----RKSGVLA----PATPHLNSPSNPSSSSVGLSTQSSQ---LVEQPEEEEK------------ 312
                |.:.::.    .||.||      |.||:|.::|.|:   |::..|||:|
Mouse   298 MLGARVNSLMVEEEDDATSHL------SGSSLGKASQVSKPVTLIDDEEEEKKLYEEWRKGQGFP 356

  Fly   313 ---REQRERGKSKSDSEAMDEDGFDYDDVDSGSGSLAGSNCSSRLTSPPITPDDEAPSTSAAASS 374
               ..|..:|:|.|.|.|.|.|..:.:||:             |:.....:.::...:......:
Mouse   357 KGEAAQGRKGRSCSMSSAQDGDDCEDEDVE-------------RIIQEWQSRNERYQAKGREQWN 408

  Fly   375 VSELDSPSSTSSSSGICSLLQSTSSSVSPRAISKPNLLSPTRQLALFKRNSPAKLRLDLESS 436
            ..|.:...::.||......|..:|:|.|   :|..::....:||....::...:.|.|.|||
Mouse   409 REEEEEEENSYSSRRRRHTLSESSASES---VSSHDIRILKQQLERSTQSRRGRYRSDSESS 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	DSPc	133..267	CDD:238073	42/149 (28%)
puc	NP_524273.1	CDC14	<193..272	CDD:225297	32/102 (31%)
Dusp27	NP_001028516.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		DSPc	133..275	CDD:238073	42/149 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..336		10/32 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..473		26/136 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	486..515
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	552..575
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	592..618
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	660..694
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	761..800
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	850..1117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810