DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment puc and DUSP9

DIOPT Version :9

Sequence 1:	NP_524273.1	Gene:	puc / 40958	FlyBaseID:	FBgn0243512	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_011529425.1	Gene:	DUSP9 / 1852	HGNCID:	3076	Length:	415	Species:	Homo sapiens

Alignment Length:	274	Identity:	83/274 - (30%)
Similarity:	125/274 - (45%)	Gaps:	62/274 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 IGANQKDYPNKRSRENLACDEVTSTTSSSTAMNGGGRTPALTRSCSSPAVYDIETHPASPVFPHL 141
            :|::..|..::..|::::|           .::..|.||        |.|....:.|.. :.|:|
Human   198 LGSDCSDAESEADRDSMSC-----------GLDSEGATP--------PPVGLRASFPVQ-ILPNL 242

  Fly   142 LLGNGRDA---DDPSSVGANCVLNVTCQSPNESHLQG-LKYMQIPASDTPHQNIKQYFQEAYDFI 202
            .||:.||:   :..:.:|...:||||...||.....| ..|.|||.||...||:.::|.||.:||
Human   243 YLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFI 307

  Fly   203 EDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELE 267
            ::|......||:||.||:|||.|:.:||:|:...|||.:||.|||..:..||||.|||||||:.|
Human   308 DEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFE 372

  Fly   268 QNLRKSGVLAPATPHLNSPSNPSSSSVGLSTQSSQLVEQPEEEEKREQRERGKSKSDSEAMDEDG 332
            ::||.                                      |:|..:|:|.....|.|.:...
Human   373 RSLRL--------------------------------------EERHSQEQGSGGQASAASNPPS 399

  Fly   333 FDYDDVDSGSGSLA 346
            |.......|:..||
Human   400 FFTTPTSDGAFELA 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	DSPc	133..267	CDD:238073	61/137 (45%)
puc	NP_524273.1	CDC14	<193..272	CDD:225297	40/78 (51%)
DUSP9	XP_011529425.1	DSP_MapKP	38..169	CDD:238723
		CDC14	224..373	CDD:225297	65/157 (41%)
		DSPc	235..372	CDD:238073	61/137 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920