Protein Alignment puc and DUSP8

DIOPT Version :10

• Sequence 1: NP_524273.1
• Gene: puc / 40958
• FlyBaseID: FBgn0243512
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_004411.2
• Gene: DUSP8 / 1850
• HGNCID: 3074
• Length: 625
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 123/453 - (27%)
• Similarity: 179/453 - (39%)
• Gaps: 102/453 - (22%)

  Fly    88 RSRENLACDEVTSTT--------SSSTAMNGGGRT------------PA--LTRSCSSPAVYDIE 130
            |....||.|...|..        .|...:.||..|            ||  |..|.|.|.: .:.
Human    94 RDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCL-PVP 157

  Fly   131 THPASPVFPHLLLGNGRDA---DDPSSVGANCVLNVTCQSPNESHLQGLKYMQIPASDTPHQNIK 192
            :...:.:.|||.||:.:|.   |..:..|.:.|||.:...|....:...::|::|.:|...:.:.
Human   158 SVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLL 222

  Fly   193 QYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNL 257
            .:..::.:||:.|:.:..:|::||.|||||||||||||:|:...:|..:||:.||..||.||||.
Human   223 PWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNF 287

  Fly   258 NFMGQLLELEQNLRKSGVLA--PATPHLNSPSNPSSSSVG-----LSTQSSQLV----------- 304
            ||:|||||.|::|:....|.  |.||. .:|..|.|.:.|     |...:|:..
Human   288 NFLGQLLEYERSLKLLAALQGDPGTPS-GTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGG 351

  Fly   305 ----------EQPEEEEKREQRERGKSKSDSEAMDEDGFDYD---DVDSGSGSLAGSNCSSRLTS 356
                      ..|......:|..||...|.....|.:.....   |:.|.             .:
Human   352 LSAGGEPPAPPTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSA-------------YA 403

  Fly   357 PPITPDDEAPSTSAAASSVSELDSPSSTSSSSGICSLLQSTSSSVSPRAISKPN----------L 411
            |...||...|.....|..:.:|||||  .::.|:.| ....|...:|.|..:|.          .
Human   404 PSRRPDGPGPPDPGEAPKLCKLDSPS--GAALGLSS-PSPDSPDAAPEARPRPRRRPRPPAGSPA 465

  Fly   412 LSPTRQLAL----FKRNSPAKLRLDLESSYAPASPIPNT-------MPWLSVPSTPVCEEAPD 463
            .||...|.|    ..|.:|   |..|.:..||..|.|..       .|.|..|.||    :||
Human   466 RSPAHSLGLNFGDAARQTP---RHGLSALSAPGLPGPGQPAGPGAWAPPLDSPGTP----SPD 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	PTP_DSP_cys	135..281	CDD:475123	57/150 (38%)
DUSP8	NP_004411.2	DSP_MapKP	10..137	CDD:238723	9/42 (21%)
		DSP_DUSP8	150..300	CDD:350493	56/150 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..586		53/240 (22%)