DRSC/TRiP Functional Genomics Resources

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Protein Alignment puc and DUSP6

DIOPT Version :9

Sequence 1:NP_524273.1 Gene:puc / 40958 FlyBaseID:FBgn0243512 Length:476 Species:Drosophila melanogaster
Sequence 2:NP_001937.2 Gene:DUSP6 / 1848 HGNCID:3072 Length:381 Species:Homo sapiens


Alignment Length:213 Identity:86/213 - (40%)
Similarity:115/213 - (53%) Gaps:15/213 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   100 STTSSSTAMNGGGRTP-ALTRSCSSPAVYDIETHPASPV--FPHLLLGNGRDA---DDPSSVGAN 158
            |:.|||...:...|.| :.|.|..||.   ..:.|:.||  .|.|.||..:|:   |.....|..
Human   173 SSDSSSDIESDLDRDPNSATDSDGSPL---SNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIK 234

  Fly   159 CVLNVTCQSPNESHLQG-LKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISR 222
            .:||||...||.....| .||.|||.||...||:.|:|.||..||::||.....||:||.|||||
Human   235 YILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISR 299

  Fly   223 SATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSGVLAPATP----HL 283
            |.|:.:||:|:..:||:.:||.:||:.:..||||.|||||||:.|:.|..|.......|    :.
Human   300 SVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYF 364

  Fly   284 NSPSNPSSSSVGLSTQSS 301
            .:|||.:...|. |.||:
Human   365 TTPSNQNVYQVD-SLQST 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pucNP_524273.1 DSPc 133..267 CDD:238073 65/139 (47%)
CDC14 <193..272 CDD:225297 41/78 (53%)
DUSP6NP_001937.2 DSP_MapKP 17..147 CDD:238723
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 176..203 9/29 (31%)
DSPc 207..344 CDD:238073 64/136 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2281
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.940

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