Protein Alignment puc and DUSP1

DIOPT Version :10

• Sequence 1: NP_524273.1
• Gene: puc / 40958
• FlyBaseID: FBgn0243512
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_004408.1
• Gene: DUSP1 / 1843
• HGNCID: 3064
• Length: 367
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 96/320 - (30%)
• Similarity: 130/320 - (40%)
• Gaps: 110/320 - (34%)

  Fly    94 ACDEVTSTTSSSTAMNGGGRTPALT----------RSCSSPAVYDIETHPASPVFPHLLLGNGRD 148
            :|.|:.|  ..||.|  |...|..|          .|||:| :|| :..|.. :.|.|.||:...
Human   131 SCPELCS--KQSTPM--GLSLPLSTSVPDSAESGCSSCSTP-LYD-QGGPVE-ILPFLYLGSAYH 188

  Fly   149 A---DDPSSVGANCVLNVTCQSPNESHLQG-LKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTG 209
            |   |...::|...::||:...||  |.:| .:|..||..|....:|..:|.||.|||:..:..|
Human   189 ASRKDMLDALGITALINVSANCPN--HFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAG 251

  Fly   210 SRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSG 274
            .||.:||.|||||||||.:||:||...:.|.||::.||..|.|||||.:||||||:.|     |.
Human   252 GRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFE-----SQ 311

  Fly   275 VLAPATPHLNSPSNPSSSSVGLSTQSSQLVEQPEEEEKREQRERGKSKSDSEAMDEDGFDYDDVD 339
            ||||
Human   312 VLAP------------------------------------------------------------- 315

  Fly   340 SGSGSLAGSNCSSRLTSPPITPDDEAPSTS------------AAASSVSELDSPSSTSSS 387
                     :||:...||.:...|...||:            :..|::|.|.||.:||.|
Human   316 ---------HCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPS 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	PTP_DSP_cys	135..281	CDD:475123	65/149 (44%)
DUSP1	NP_004408.1	DSP_MapKP	7..136	CDD:238723	2/4 (50%)
		DSP_DUSP1	174..324	CDD:350486	68/227 (30%)