Protein Alignment puc and DUSP12

DIOPT Version :10

• Sequence 1: NP_524273.1
• Gene: puc / 40958
• FlyBaseID: FBgn0243512
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_009171.1
• Gene: DUSP12 / 11266
• HGNCID: 3067
• Length: 340
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 75/292 - (25%)
• Similarity: 117/292 - (40%)
• Gaps: 55/292 - (18%)

  Fly   115 PALTR-SCSSPAVYDIETHPASPVFPHLLLGNGRDADDPS---SVGANCVLNVTCQSPN---ESH 172
            |:.:| ||:...:         .|.|.|..|......:|.   ..|...||.|..:.|:   ...
Human    16 PSASRVSCAGQML---------EVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPG 71

  Fly   173 LQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSL 237
            ::.|..:.:||.|.|..::..:......||..||..|..||:|||||:|||..|..|::|:...|
Human    72 VEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQL 136

  Fly   238 SLLEAYKLVKVARPIISPNLNF---------MGQLLELEQNLRKSGVLAPAT---PHL-NSPS-- 287
            ...:||:.:::.:|....|..|         ||..::....:.|...|...|   |.| |.|.
Human   137 PFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQYRLQKVTEKYPELQNLPQEL 201

  Fly   288 ---NPSSSSVGLSTQSSQLVEQPEEEEKREQRERGKSKSDSEAMDEDGFDYDDVDSGSGSLAGSN 349
               :|::.|.||         :.|...|..:..|...:|.|..         |...|||.:|.::
Human   202 FAVDPTTVSQGL---------KDEVLYKCRKCRRSLFRSSSIL---------DHREGSGPIAFAH 248

  Fly   350 CSSRLT-SPPITPDDEAPSTSAAASSVSELDS 380
              .|:| |..:|...:|..||.....|..::|
Human   249 --KRMTPSSMLTTGRQAQCTSYFIEPVQWMES 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	PTP_DSP_cys	135..281	CDD:475123	44/163 (27%)
DUSP12	NP_009171.1	DSP_DUSP12	27..173	CDD:350370	41/154 (27%)