Protein Alignment puc and DUSP10

DIOPT Version :9

• Sequence 1: NP_524273.1
• Gene: puc / 40958
• FlyBaseID: FBgn0243512
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_009138.1
• Gene: DUSP10 / 11221
• HGNCID: 3065
• Length: 482
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 118/394 - (29%)
• Similarity: 172/394 - (43%)
• Gaps: 126/394 - (31%)

  Fly     6 ETQSSSNNNSNNTTTATSTAR--------NNNSHNGRCE-CDGDGDSVSHIQSEM---------- 51
            :||:.:   :..||||..|:.        |||.:.|... ..|.|..||....::
Human    93 QTQAIA---AGTTTTAIGTSTTCPANQMVNNNENTGSLSPSSGVGSPVSGTPKQLASIKIIYPND 154

  Fly    52 ---------KMRIKREAPCLLLFMPIQNTNNNNRIGA---NQKDYPNKR---------------- 88
                     |..:..:.|.::...|....|.::..||   |..|..::|
Human   155 LAKKMTKCSKSHLPSQGPVIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCR 219

  Fly    89 ----------SRENLACDEVTSTTS-----------------------------SSTAMN----- 109
                      |:|.:..||.|:..|                             ||...|
Human   220 EGKDSFKRIFSKEIIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLC 284

  Fly   110 ------------GGGRTPALTRSCSS------PAVYDIETHPASPVFPHLLLGNGRDADDPSS-- 154
                        |||.:.|     ||      |...|||....:|:.|.|.|||.:||.|..:
Human   285 DNSLQLQECREVGGGASAA-----SSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQ 344

  Fly   155 -VGANCVLNVTCQSPNESHLQGL-KYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCH 217
             :....|:|||...|...:.:|| .|.::||:|:..||::|||:||::|||:|.:.|..:|:||.
Human   345 RLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQ 409

  Fly   218 AGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSGVLAPATPH 282
            ||:||||||.|||:|::..:::.:|||.||..||||||||||||||||.|::| .:||    ||.
Human   410 AGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL-NNGV----TPR 469

  Fly   283 LNSP 286
            :.:|
Human   470 ILTP 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	DSPc	133..267	CDD:238073	68/137 (50%)
		CDC14	<193..272	CDD:225297	48/78 (62%)
DUSP10	NP_009138.1	DSP_MapKP	149..284	CDD:238723	18/134 (13%)
		Interaction with MAP kinases	199..215		1/15 (7%)
		DSPc	321..459	CDD:238073	68/137 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	127	1.000	Domainoid score	I5398
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3731
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	1	1.000	-	-		FOG0006093
OrthoInspector	1	1.000	-	-		oto89824
orthoMCL	1	0.900	-	-		OOG6_107759
Panther	1	1.100	-	-	LDO	PTHR10159
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2281
SonicParanoid	1	1.000	-	-		X5190
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.800