DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment puc and dusp8b

DIOPT Version :9

Sequence 1:	NP_524273.1	Gene:	puc / 40958	FlyBaseID:	FBgn0243512	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_002665347.3	Gene:	dusp8b / 100330259	ZFINID:	ZDB-GENE-120914-3	Length:	499	Species:	Danio rerio

Alignment Length:	357	Identity:	102/357 - (28%)
Similarity:	151/357 - (42%)	Gaps:	108/357 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 PA--LTRSCSSPAVYDIETHPASPVFPHLLLGNGRDA---DDPSSVGANCVLNV--TCQSP---N 169
            ||  |..|.|.|.:......| :.:.|||.||:.||.   :..|..|...|||.  ||..|   :
Zfish    40 PASILPLSLSQPCLPVANIGP-TRILPHLYLGSQRDVLNKEVMSQNGITYVLNASNTCPKPDFIS 103

  Fly   170 ESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRY 234
            |:|     :|:||.:|:..:.:..:.::..:||:.|:.:..||::||.|||||||||||||:|:.
Zfish   104 ENH-----FMRIPVNDSYCEKLLPWLEKTNEFIDKAKVSNCRVIVHCLAGISRSATIAIAYIMKT 163

  Fly   235 KSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNL--RKSGVLAPATPHLNSPSNPSSSSVGLS 297
            ..||..:||:.||..||.||||.||:|||||.|:.|  :||         |..|....:|:|
Zfish   164 MGLSSDDAYRFVKDRRPSISPNFNFLGQLLEFERGLEMKKS---------LPCPIRMEASTV--- 216

  Fly   298 TQSSQLVEQPEEEEKREQRERGKSKSDSEAMDEDGFDYDDVDSGSGSLAGSNCSSRLTSPPITPD 362
                           :|..|..|.::|.:.                       :|:.|...:.|
Zfish   217 ---------------KEVTEIRKMENDDQR-----------------------TSQTTEITVNP- 242

  Fly   363 DEAPSTSAAASSVSELDSPSSTSSSSGICSLLQSTSSSVSPRAISKPNLLSPTRQLALFKRNSPA 427
                              ||.||....:.||..||...:..:.:.                   .
Zfish   243 ------------------PSPTSLQKDLSSLHLSTEKILQNKRLK-------------------C 270

  Fly   428 KLRLDLESSYAPASPIPNTMPWLSVPSTP-VC 458
            ...||::|.|: :||..|:.|.....:|| :|
Zfish   271 SFSLDIKSVYS-SSPNHNSSPNSDSENTPKIC 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
puc	NP_524273.1	DSPc	133..267	CDD:238073	62/141 (44%)
puc	NP_524273.1	CDC14	<193..272	CDD:225297	42/80 (53%)
dusp8b	XP_002665347.3	RHOD	<13..36	CDD:294087
dusp8b	XP_002665347.3	DSPc	59..196	CDD:238073	62/142 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010