DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7900 and DUR1,2

DIOPT Version :9

Sequence 1:	NP_001097707.1	Gene:	CG7900 / 40957	FlyBaseID:	FBgn0037548	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_009767.1	Gene:	DUR1,2 / 852507	SGDID:	S000000412	Length:	1835	Species:	Saccharomyces cerevisiae

Alignment Length:	469	Identity:	108/469 - (23%)
Similarity:	189/469 - (40%)	Gaps:	85/469 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 LNALIESRFTAALEEA----TETDDLIASCQTAAEVEKLFEERPLLGLPVTIKESCALEGM--TF 139
            |.:|::|:..|.::.|    ...::|:...|.....|.. |..||.|:|:.:|::..:.|:  |.
Yeast    36 LESLLDSQNVAPVDNAWISLISKENLLHQFQILKSRENK-ETLPLYGVPIAVKDNIDVRGLPTTA 99

  Fly   140 AVGSLSRKNIKAEADGEAVKRLKLAGAIPLLVSATPEYCFSIETDTLLNGRCLNPYDSERTSGGS 204
            |..|.:.:..|   |.:.|:.|:.||||.:..:...::...:.......|:....:..|..||||
Yeast   100 ACPSFAYEPSK---DSKVVELLRNAGAIIVGKTNLDQFATGLVGTRSPYGKTPCAFSKEHVSGGS 161

  Fly   205 SGGEGSLNGAGASLFGIGSDIGGSIRIPSLYCGIFGHKPSGGVVSVKGHFP--NSLDPNIGHYLV 267
            |.|..|:...|.....:|:|..||.|:|:....:.|.||:.||.|.:|..|  .|||
Yeast   162 SAGSASVVARGIVPIALGTDTAGSGRVPAALNNLIGLKPTKGVFSCQGVVPACKSLD-------- 218

  Fly   268 EGPITRFAEDLSE---LLQVMAGKENSSKLRLNEPVQLNQIKVQYALAFEGINGWMHMAVDKDIT 329
              .::.||.:||:   ..::|...:..:. ..:.|...|.:|        ..:..:.:|:.|:|.
Yeast   219 --CVSIFALNLSDAERCFRIMCQPDPDND-EYSRPYVSNPLK--------KFSSNVTIAIPKNIP 272

  Fly   330 G--------AICKATTHLKTLGLNVKKVKLPNLENSVEMALSGIAG-------QDLMDYLLTDEN 379
            .        ....|..:|...|.||.::   :.|..:|:|.....|       |.:..:|  |..
Yeast   273 WYGETKNPVLFSNAVENLSRTGANVIEI---DFEPLLELARCLYEGTWVAERYQAIQSFL--DSK 332

  Fly   380 PEGSGKVRETV-WEIVKSVRGHSKYT-TNALIFELMRRTGAFMSQSKINQYMKETRELIGEFENL 442
            |.     :|:: ..::..:.|..||: .:...||..|                  :.::.:...|
Yeast   333 PP-----KESLDPTVISIIEGAKKYSAVDCFSFEYKR------------------QGILQKVRRL 374

  Fly   443 LGDNGVLLFPTLNLPAPRHKWS-----ILSLWGVDYTLMFNVLGLPVTHVPMGLNERGLPIGLSV 502
            |....||..||..|.....:.:     :.|..|. :|...|:..|....||.|..:.|||.|:::
Yeast   375 LESVDVLCVPTCPLNPTMQQVADEPVLVNSRQGT-WTNFVNLADLAALAVPAGFRDDGLPNGITL 438

  Fly   503 IGAPNQDRLCLRVA 516
            ||....|...|.:|
Yeast   439 IGKKFTDYALLELA 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7900	NP_001097707.1	PRK07488	44..530	CDD:236030	108/469 (23%)
CG7900	NP_001097707.1	GatA	47..531	CDD:223232	108/469 (23%)
DUR1,2	NP_009767.1	allophanate_hyd	49..620	CDD:274265	104/456 (23%)
DUR1,2	NP_009767.1	urea_carbox	633..1832	CDD:274264
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810