DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7900 and faah2b

DIOPT Version :9

Sequence 1:	NP_001097707.1	Gene:	CG7900 / 40957	FlyBaseID:	FBgn0037548	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001070930.1	Gene:	faah2b / 768298	ZFINID:	ZDB-GENE-061027-358	Length:	526	Species:	Danio rerio

Alignment Length:	539	Identity:	215/539 - (39%)
Similarity:	309/539 - (57%)	Gaps:	45/539 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IVILVKVIALIVSPLLEAFVYRPKSKRTLIPPIRSRLLTLSVQELRRRLQSRQLTSVELVRTYIE 72
            :::||..:.|.:..||.....|||.    :|||.:.|||||..:|..:::..:::|||:|:.||:
Zfish    13 LLVLVSGLFLALFRLLSPGTKRPKH----LPPITNPLLTLSAVQLAEKIRRGEVSSVEVVQAYID 73

  Fly    73 RIEAVNKHLNALIESRFTAALEEATETDDLIASCQTAAEVEKLFEERPLLGLPVTIKESCALEGM 137
            ||:.||..|||||:.||:|||.||...|.||.......||  |..:.||||:|:::|||..|:||
Zfish    74 RIQEVNPLLNALIKDRFSAALLEAARADKLIKEENGGEEV--LRNQFPLLGVPMSVKESFGLQGM 136

  Fly   138 TFAVGSLSRKNIKAEADGEAVKRLKLAGAIPLLVSATPEYCFSIETDTLLNGRCLNPYDSERTSG 202
            ..:.|..||..:.|..|...|..||.||||||.|:.|.|.|..:|::..|.|...|||:.||..|
Zfish   137 PNSGGLKSRGKVLASVDAPPVALLKRAGAIPLGVTNTSELCMWMESNNHLYGITSNPYNLERICG 201

  Fly   203 GSSGGEGSLNGAGASLFGIGSDIGGSIRIPSLYCGIFGHKPSGGVVSVKGHFP--NSLDPNIGHY 265
            ||||||||:.|.|||:||||||||||||:|..:.||||||||.||||....||  :.|.   ..|
Zfish   202 GSSGGEGSIIGGGASVFGIGSDIGGSIRMPCFFNGIFGHKPSRGVVSNDNQFPRCSGLQ---NEY 263

  Fly   266 LVEGPITRFAEDLSELLQVMAGKENSSKLRLNEPVQLNQIKVQYALAFEGINGWMHMAVDKDITG 330
            ...||:.|:||||..||::||| ..:.||.|::.|.|.:::. :.:..:| ...:...||:.:..
Zfish   264 TGSGPMCRYAEDLLPLLKIMAG-PTADKLTLSKAVDLKKLRF-FTIVDDG-GSPLTSPVDRQLVE 325

  Fly   331 AICKATTHLKT-LGLNVKKVKLPNLENSVEMALSGIAGQDLMDYLLTDENPEGSGKVRET----- 389
            ...:....|:. ||:.|::|..|.|:.|.:          :.|..|.  .|:..||..|.
Zfish   326 VQKRVAARLEADLGVTVQEVNFPQLKYSYQ----------IWDTFLA--LPDKDGKPPEAFVELM 378

  Fly   390 --------VWEIVKSVRGHSKYTTNALIFELMRRTGAFMSQSKINQY-MKETRELIGEFENLLGD 445
                    |||::|.:.|.|::|..|:...||..:    ..||.::: :|:..:|..|.|:|||.
Zfish   379 ADGGSVWPVWELIKRIFGRSEHTVAAIGLALMESS----HSSKSSEFILKQKEDLQREMEDLLGT 439

  Fly   446 NGVLLFPTLNLPAPRHKWSILSLWGVDYTLMFNVLGLPVTHVPMGLNERGLPIGLSVIGAPNQDR 510
            :||||:|:..|.||:|...:...:...||.:.|:||||||..|:||::..||:|:.|:....||.
Zfish   440 DGVLLYPSHPLLAPKHHHPLFMPFNFSYTGILNILGLPVTQCPLGLSKERLPLGVQVVAGLCQDH 504

  Fly   511 LCLRVAVELERAFGGWKPP 529
            |.|.:|:.||:|||||..|
Zfish   505 LTLAMALYLEKAFGGWVDP 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7900	NP_001097707.1	PRK07488	44..530	CDD:236030	204/503 (41%)
CG7900	NP_001097707.1	GatA	47..531	CDD:223232	201/500 (40%)
faah2b	NP_001070930.1	PRK07488	45..518	CDD:236030	199/496 (40%)
faah2b	NP_001070930.1	GatA	48..523	CDD:223232	200/498 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D852596at2759
OrthoFinder	1	1.000	-	-		FOG0002245
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43372
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.880