DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7900 and GatA

DIOPT Version :9

Sequence 1:	NP_001097707.1	Gene:	CG7900 / 40957	FlyBaseID:	FBgn0037548	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_650775.2	Gene:	GatA / 42283	FlyBaseID:	FBgn0260779	Length:	508	Species:	Drosophila melanogaster

Alignment Length:	538	Identity:	139/538 - (25%)
Similarity:	224/538 - (41%)	Gaps:	110/538 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RLLTLSVQELRRRLQSRQLTSVELVRTYIERIEAVN-KHLNALIESRFTAALEEATETDDLIASC 106
            |.|..|:::|.......||:...:....::  :|:. |.|||.:  |.|.  |:|.
  Fly     3 RHLQWSIKQLTASYSDGQLSPRRVTEDALQ--DALRWKTLNAFV--RLTP--EQAG--------- 52

  Fly   107 QTAAEVEKLFEER----PLLGLPVTIKESCALEGMTFAVGSLSRKNIKAEADGEAVKRLKLAGAI 167
            |.|.:.|:.::.|    .|.|:.:.||::...:.:.....|...::.....|.....|||.|||:
  Fly    53 QQAQDAEQRYKLRQPISDLDGVTIAIKDNFCTKDVHTTCASRMLQDFVPPYDATVCSRLKQAGAV 117

  Fly   168 PLLVSATPEYCFSIETDTLLNGRCLNPY------DSERTSGGSSGGEGSLNGAGASLFGIGSDIG 226
            .|..:...::.....|...|.|...|.:      |..|.:||||||..|...||.....||||.|
  Fly   118 ILGKTNMDQFAMGAGTVDSLYGPTKNIWSEDLNKDHWRIAGGSSGGSASAVAAGLCYAAIGSDTG 182

  Fly   227 GSIRIPSLYCGIFGHKPSGGVVSVKGHFP--NSLDPNIGHYLVEGPITRFAEDLSELLQVMAGKE 289
            ||.|.|:.|||:.|.||:.|:||..|..|  ||:|       |.|...|...|...:|..:||.:
  Fly   183 GSTRNPASYCGVVGLKPTYGLVSRHGLIPLVNSMD-------VPGIFARSVSDCVAVLNTVAGPD 240

  Fly   290 NSSKLRLNEP-----------VQLNQIKVQ-------YALAFEGINGWMHMAVDKDITGAICKAT 336
            ......:.:|           :.|:.:::.       :.|:.|.:..|..:|   |:
  Fly   241 KLDSTTIRQPFTRLHLPEVGQIDLSTVRIGIPKEYHCHGLSAEVLETWSKVA---DL-------- 294

  Fly   337 THLKTLGLNVKKVKLPN---------LENSVEMALSGIAGQDLMDY--LLTDENPEGSGKVRETV 390
              |:..|.:|::|.|||         :.|..|:| |.:|..|.::|  ..|||      :..|.:
  Fly   295 --LECSGASVRQVSLPNTAASIFVYTILNQCEVA-SNMARYDGIEYGHRATDE------RSTEQL 350

  Fly   391 WEIVKSVRGHSKYTTNALIFELMRRTGAFMSQSK-INQYMKE---TRELIGE-FENLLGDNG--- 447
            :.:.::...:....|..|       ||.|:...| .:.|.::   .|.||.| |..:...:.
  Fly   351 YALSRAEGFNDVVKTRIL-------TGNFLLLKKNYDHYFEKALRVRRLIAEDFARVFDSSAKEE 408

  Fly   448 ---VLLFPTLNLPAPRHKWSILSLWGVDY-------TLMFNVLGLPVTHVPMGLNERGLPIGLSV 502
               :||.||....||.:| ...||...|.       |...|:.|:|...:|:.|::.|||:.|.:
  Fly   409 RVDILLTPTTLTEAPLYK-DFASLTNRDQCAVQDFCTQPANMAGIPAVSIPIRLSQAGLPLSLQL 472

  Fly   503 IGAPNQDRLCLRVAVELE 520
            :.....::|.|.||..:|
  Fly   473 MSNSLNEQLLLTVARWIE 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7900	NP_001097707.1	PRK07488	44..530	CDD:236030	138/537 (26%)
CG7900	NP_001097707.1	GatA	47..531	CDD:223232	137/534 (26%)
GatA	NP_650775.2	PRK07488	8..491	CDD:236030	137/533 (26%)
GatA	NP_650775.2	gatA	18..490	CDD:234572	134/521 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0154
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.729574	Normalized mean entropy	S1380
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.690