DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7900 and CG8839

DIOPT Version :9

Sequence 1:	NP_001097707.1	Gene:	CG7900 / 40957	FlyBaseID:	FBgn0037548	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_610764.1	Gene:	CG8839 / 36340	FlyBaseID:	FBgn0033717	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	205/536 - (38%)
Similarity:	304/536 - (56%)	Gaps:	30/536 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VILVKVIALIVSPLLEA---FVYR--PKSKRTLIPPIRSRLLTLSVQELRRRLQSRQLTSVELVR 68
            |.|.:.|...:..:|:|   ||:|  ...|...:|||...:|..|...|.|:::.::|:||:::.
  Fly     5 VPLTQAIGGYIFGILQACIRFVFRLIYGQKGESVPPITDAILLESATSLARKIRKQELSSVQVLE 69

  Fly    69 TYIERIEAVNKHLNALIESRFTAALEEATETDDLIASCQTAAEVEKLFEERPLLGLPVTIKESCA 133
            ::|.||:.||..||.:::.|:..||:||.|.|.||.|.|.:  .|:|.:|:|.||:|:|.|:..:
  Fly    70 SFIRRIKEVNPILNCVVDERYDQALKEAAEADALIKSGQYS--TEELEKEKPFLGVPITTKDCIS 132

  Fly   134 LEGMTFAVGSLSRKNIKAEADGEAVKRLKLAGAIPLLVSATPEYCFSIETDTLLNGRCLNPYDSE 198
            ::||....|...|::::|..|.:|:..::.|||||:.::...|.|...|::..::||..|.||:.
  Fly   133 VKGMLHTAGLFERRDVRAARDADAMALMRKAGAIPIALTNVSEVCMWWESNNTVHGRTRNAYDTN 197

  Fly   199 RTSGGSSGGEGSLNGAGASLFGIGSDIGGSIRIPSLYCGIFGHKPSGGVVSVKGHFPNSLDPNIG 263
            |..||||||||.:..|.||.||:|||||||||:|:.:.||||||||..|||..|.||........
  Fly   198 RIVGGSSGGEGCIQSAAASAFGLGSDIGGSIRMPAFFNGIFGHKPSKLVVSNVGQFPAPFSAEQN 262

  Fly   264 HYLVEGPITRFAEDLSELLQVMAGKENSSKLRLNEPVQLNQIKVQYALAFEGINGWMHMAVDKDI 328
            .:|..||::||||||..:|::||| |.::.|.|:|.|.|.::|..|..:..|  |.:..|||.|:
  Fly   263 SFLGLGPMSRFAEDLRPMLKIMAG-EKAALLNLDEDVDLTKMKFFYQESDGG--GRLVSAVDPDL 324

  Fly   329 TGAICKATTHLKTLGLN--VKKVKLPNLENSVEMALSGIAGQDLMDYLLTDENPEG----SGKVR 387
            ..|:.:...||:....|  |::::||:...|..:..:.          :.|::..|    .|.:.
  Fly   325 REAMNRVAQHLREKFGNQKVERIQLPHFRQSAAIWFAN----------MRDDSGHGFAYQLGNLN 379

  Fly   388 ---ETVWEIVKSVRGHSKYTTNALIFELMRRTGAFMSQSKINQYMKETRELIGEFENLLGDNGVL 449
               .|..|:.|...|.||:|...|...:|..........|.:..:::..||..|.::||||||||
  Fly   380 HDINTYLELFKWFFGASKHTFIGLSTAIMDSAQCKHGSPKYDHLVRKRNELREELQSLLGDNGVL 444

  Fly   450 LFPTLNLPAPRHKWSILSLWGVDYTLMFNVLGLPVTHVPMG-LNERGLPIGLSVIGAPNQDRLCL 513
            ::||....||.|...|.......||.:.||||.|.|.||:| |...|||:|:.:|...|||||||
  Fly   445 IYPTHPTVAPYHNEPITRPINFAYTGIVNVLGFPATAVPLGKLGSEGLPLGVQIIANFNQDRLCL 509

  Fly   514 RVAVELERAFGGWKPP 529
            .||.|||||||||..|
  Fly   510 AVAEELERAFGGWAKP 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7900	NP_001097707.1	PRK07488	44..530	CDD:236030	193/496 (39%)
CG7900	NP_001097707.1	GatA	47..531	CDD:223232	192/493 (39%)
CG8839	NP_610764.1	GatA	42..525	CDD:223232	192/497 (39%)
CG8839	NP_610764.1	PRK07488	49..520	CDD:236030	187/485 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440862
Domainoid	1	1.000	107	1.000	Domainoid score	I6507
eggNOG	1	0.900	-	-		E1_COG0154
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	142	1.000	Inparanoid score	I4451
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D54749at33392
OrthoFinder	1	1.000	-	-		FOG0002245
OrthoInspector	1	1.000	-	-		otm42825
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43372
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X256
	10	9.900