Protein Alignment CG7900 and FAAH

DIOPT Version :10

• Sequence 1: NP_001097707.1
• Gene: CG7900 / 40957
• FlyBaseID: FBgn0037548
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001432.2
• Gene: FAAH / 2166
• HGNCID: 3553
• Length: 579
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 142/547 - (25%)
• Similarity: 235/547 - (42%)
• Gaps: 119/547 - (21%)

  Fly    44 LLTLSVQELRRRLQSRQLTSVELVRTYIERIEAVNKHLNALIESRFTAALEEATETDDLIASCQT 108
            ||.|.:.:|.::|.||:|....::.||:.:...|||..|.:               ...:|.|:|
Human    74 LLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCV---------------TSYLADCET 123

  Fly   109 AAEVEKLFEERPLLGLPVTIKESCALEGMTFAVGSLSRKNIKAEADGEAVKRLKLAGAIPLLVSA 173
              ::.:...:..|.|:||::||....:|....:|....:.:.||.|...|..|||.||:|.:.:.
Human   124 --QLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTN 186

  Fly   174 TPEYCFSIETDTLLNGRCLNPYDSERTSGGSSGGEGSLNGAGASLFGIGSDIGGSIRIPSLYCGI 238
            .|:..||.:....|.|:.:||:.|.::.||||||||:|.|:|.|..|:|:|||||||.||.:|||
Human   187 VPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGI 251

  Fly   239 FGHKPSGGVVSVKGHFPNSLDPNIGHYLVEGPITRFAEDLSELLQVMAGKENSSKLRLNEPV--- 300
            .|.||:|..:|..| ....:.......|..||:.|..|.|:..|:.:..::   ..||:..|
Human   252 CGLKPTGNRLSKSG-LKGCVYGQEAVRLSVGPMARDVESLALCLRALLCED---MFRLDPTVPPL 312

  Fly   301 --------QLNQIKVQYALAFEGINGWMHMAVDKDITGAICKATTHLKTLGLNVKKVKLPNLENS 357
                    ....::|.|   :|..|..|....   :..|:.:....|:..|..:......|:.::
Human   313 PFREEVYTSSQPLRVGY---YETDNYTMPSPA---MRRAVLETKQSLEAAGHTLVPFLPSNIPHA 371

  Fly   358 VE-MALSGIAGQ-----------DLMDYLLTDENPEGSGKVRETVWEIVKSVRGHSKYTTNALIF 410
            :| ::..|:...           |.:|..|.|         ..::.::.:.::|...:    |:.
Human   372 LETLSTGGLFSDGGHTFLQNFKGDFVDPCLGD---------LVSILKLPQWLKGLLAF----LVK 423

  Fly   411 ELMRRTGAFMS-------------QSKINQYMKETRELIGEFENLLGDNGV----LLFPTLNLPA 458
            .|:.|..||:|             |.:|..|.|   .:|.::..|  |..|    :|.|.|:|.|
Human   424 PLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRK---TVIAQWRAL--DLDVVLTPMLAPALDLNA 483

  Fly   459 PRHKWSILSLWGVDYTLMFNVLGLPVTHVPM----------------------------GLNER- 494
            |..     :...|.||:::|.|..|...||:                            |:.:.
Human   484 PGR-----ATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMKKSV 543

  Fly   495 GLPIGLSVIGAPNQDRLCLRVAVELER 521
            |||:.:..:..|.|:.||||...|:||
Human   544 GLPVAVQCVALPWQEELCLRFMREVER 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7900	NP_001097707.1	GatA	42..531	CDD:439924	142/547 (26%)
FAAH	NP_001432.2	Amidase	95..562	CDD:396144	128/516 (25%)