DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7900 and Faah

DIOPT Version :9

Sequence 1:	NP_001097707.1	Gene:	CG7900 / 40957	FlyBaseID:	FBgn0037548	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001356055.1	Gene:	Faah / 100911581	RGDID:	61808	Length:	579	Species:	Rattus norvegicus

Alignment Length:	547	Identity:	143/547 - (26%)
Similarity:	238/547 - (43%)	Gaps:	103/547 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LLTLSVQELRRRLQSRQLTSVELVRTYIERIEAVNKHLNALIESRFTAALEEATETDDLIASCQT 108
            ||||.:.:|.::|||.:|:...:..||:.:...|||..|.:               ...:..|:|
  Rat    74 LLTLPLLQLVQKLQSGELSPEAVFFTYLGKAWEVNKGTNCV---------------TSYLTDCET 123

  Fly   109 AAEVEKLFEERPLLGLPVTIKESCALEGMTFAVGSLSRKNIKAEADGEAVKRLKLAGAIPLLVSA 173
              ::.:...:..|.|:||::||..:.:|....:|....:.:.:|:|...|:.|||.||:|.:.:.
  Rat   124 --QLSQAPRQGLLYGVPVSLKECFSYKGHDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTN 186

  Fly   174 TPEYCFSIETDTLLNGRCLNPYDSERTSGGSSGGEGSLNGAGASLFGIGSDIGGSIRIPSLYCGI 238
            .|:...|.:....|.|:.:||:.|.::.||||||||:|.|:|.|..|:|:|||||||.||.:|||
  Rat   187 VPQSMLSFDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGI 251

  Fly   239 FGHKPSGGVVSVKGHFPNSLDPNIGHYLVEGPITRFAEDLSELLQVMAGKE------NSSKLRLN 297
            .|.||:|..:|..| ....:.......|..||:.|..|.|:..|:.:..:.      ....|...
  Rat   252 CGLKPTGNRLSKSG-LKGCVYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFR 315

  Fly   298 EPVQLNQ--IKVQYALAFEGINGWMHMAVDKDITGAICKATTHLKTLGLNVKKVKLPNLENSVEM 360
            |.|..:.  ::|.|   :|..|..|....   :..|:.:....|:..|..:    :|.|.|::..
  Rat   316 EEVYRSSRPLRVGY---YETDNYTMPSPA---MRRALIETKQRLEAAGHTL----IPFLPNNIPY 370

  Fly   361 ALSGIAGQDLM-----DYLLTDENPEGSGKVRETVWEIVKSVRGHS--KYTTNALIFELMRRTGA 418
            ||..::...|.     .:|   :|.:|. .|...:.:::..:|..|  |...:.|:..|..|..|
  Rat   371 ALEVLSAGGLFSDGGRSFL---QNFKGD-FVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAA 431

  Fly   419 FMS-------------QSKINQYMKETRELIGEFENLLGDNGVLLF----PTLNLPAPRHKWSIL 466
            |::             |.:|..|   .:.:|.:::.:..|  |||.    |.|:|..|......:
  Rat   432 FLNSMRPRSAEKLWKLQHEIEMY---RQSVIAQWKAMNLD--VLLTPMLGPALDLNTPGRATGAI 491

  Fly   467 SLWGVDYTLMFNVLGLPVTHVPMGL-----------------------------NERGLPIGLSV 502
            |     ||:::|.|..|...||:..                             |..|||:.:..
  Rat   492 S-----YTVLYNCLDFPAGVVPVTTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQC 551

  Fly   503 IGAPNQDRLCLRVAVELERAFGGWKPP 529
            :..|.|:.||||...|:|:.....|.|
  Rat   552 VALPWQEELCLRFMREVEQLMTPQKQP 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7900	NP_001097707.1	PRK07488	44..530	CDD:236030	143/547 (26%)
CG7900	NP_001097707.1	GatA	47..531	CDD:223232	140/544 (26%)
Faah	NP_001356055.1	Amidase	95..562	CDD:418511	127/508 (25%)
Faah	NP_001356055.1	Substrate binding	238..241		2/2 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336612
Domainoid	1	1.000	110	1.000	Domainoid score	I6159
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4439
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D438196at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44893
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.900