DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7900 and faah2

DIOPT Version :9

Sequence 1:	NP_001097707.1	Gene:	CG7900 / 40957	FlyBaseID:	FBgn0037548	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	XP_002940451.1	Gene:	faah2 / 100488850	XenbaseID:	XB-GENE-6036595	Length:	527	Species:	Xenopus tropicalis

Alignment Length:	539	Identity:	196/539 - (36%)
Similarity:	300/539 - (55%)	Gaps:	29/539 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEIFLRLIVILVKVIA---LIVSPLLEAFVYRPKSKRTLIPPIRSRLLTLSVQELRRRLQSRQLT 62
            |.:..||:|..::.::   |....||..|...|....   ||: ..||.:...:|..:::.|:|.
Frog     1 MRLLHRLLVCTLRGLSWALLGFIRLLSVFSRDPPCPD---PPL-DPLLFIPATKLADKIRRRELQ 61

  Fly    63 SVELVRTYIERIEAVNKHLNALIESRFTAALEEATETDDLIASCQTAAEVEKLFEERPLLGLPVT 127
            |..:|:.:|.||..||..|||::..||..||:||...|:|::| .|..| |.|.|:.||||:|.|
Frog    62 SSAVVQAFISRIRQVNPALNAVVCERFDQALQEARNVDELVSS-GTENE-ETLREKYPLLGVPFT 124

  Fly   128 IKESCALEGMTFAVGSLSRKNIKAEADGEAVKRLKLAGAIPLLVSATPEYCFSIETDTLLNGRCL 192
            :||:.||:||..:.|.|||:.:.:::|...|.|:|.||.|||.|:...|.|...|:...:.|:..
Frog   125 VKEAFALQGMPQSSGLLSRRFVCSQSDAVVVSRIKSAGGIPLGVTNCSELCMWYESSNKVYGKTR 189

  Fly   193 NPYDSERTSGGSSGGEGSLNGAGASLFGIGSDIGGSIRIPSLYCGIFGHKPSGGVVSVKGHFPNS 257
            |||:.:...||||||||.:.....|:.|:|||||||||:|:.:.||:|||.:..:|...|.||
Frog   190 NPYNPQHIVGGSSGGEGCILATAGSVIGVGSDIGGSIRMPAFFNGIYGHKATADIVPNDGQFP-- 252

  Fly   258 LDPNI-GHYLVEGPITRFAEDLSELLQVMAGKENSSKLRLNEPVQLNQIKVQYALAFEGINGWMH 321
            :|... ..:|..||:.|:|.||..||:|||| |::.:|.|:..|:|:.::. :::..:| ...:.
Frog   253 IDDGCRREFLCTGPMCRYAGDLIPLLKVMAG-ESAGRLHLDREVKLSSLRF-FSMEHDG-GSPIV 314

  Fly   322 MAVDKDITGAICKATTHL-KTLGLNVKKVKLPNLEN-----SVEMALSGIAGQDLMDYLLTDENP 380
            .||||::..|..:...|| :.||:.|::|.:.||..     |..|:..|...|...|.:
Frog   315 SAVDKELVQAQRRVVEHLERELGVTVQQVSIYNLRYSFPIWSAMMSQDGGEEQSFADLM------ 373

  Fly   381 EGSGKVRETVWEIVKSVRGHSKYTTNALIFELMRRTGAFMSQSKINQYMKETRELIGEFENLLGD 445
             |.||.....||::|.:.|.||:|...:...|..:...:.:|...|. :|:.|.|..|...:|||
Frog   374 -GDGKGFWPFWELLKWMFGISKHTLPGIALALTEKMAHWNTQGNENM-IKKARSLRQEISTMLGD 436

  Fly   446 NGVLLFPTLNLPAPRHKWSILSLWGVDYTLMFNVLGLPVTHVPMGLNERGLPIGLSVIGAPNQDR 510
            :|:|::|:....||||...|...:...||.:||||.||||..|:||:..|||:|:.::.:...||
Frog   437 DGILIYPSHPKIAPRHHEPIAMPFNFAYTGIFNVLALPVTQCPVGLSRDGLPLGIQLVASHYNDR 501

  Fly   511 LCLRVAVELERAFGGWKPP 529
            |.|.:|..||:...||.||
Frog   502 LTLALAQYLEKTMVGWIPP 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7900	NP_001097707.1	PRK07488	44..530	CDD:236030	185/493 (38%)
CG7900	NP_001097707.1	GatA	47..531	CDD:223232	183/490 (37%)
faah2	XP_002940451.1	Amidase	64..504	CDD:388496	171/454 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D852596at2759
OrthoFinder	1	1.000	-	-		FOG0002245
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920