Protein Alignment CG7910 and AMD2

DIOPT Version :9

• Sequence 1: NP_001287222.1
• Gene: CG7910 / 40956
• FlyBaseID: FBgn0037547
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_010528.3
• Gene: AMD2 / 851829
• SGDID: S000002650
• Length: 549
• Species: Saccharomyces cerevisiae
• Alignment Length: 567
• Identity: 134/567 - (23%)
• Similarity: 223/567 - (39%)
• Gaps: 159/567 - (28%)

  Fly    35 SGIRNPLLKKSVVELVTQLRRGEITSVELVSAYIARVQEVNPSLNAVVEDRFEAALQDAKLADQF 99
            |...|.:...:::.|...|...|::..|:.:|:..|...::..:|.:.|..|..||   :|||.:
Yeast    52 SSSENQITHSTIMALRQALEAKELSCHEITAAFCHRAALIHQVVNCLSEIMFSEAL---RLADYY 113

  Fly   100 IEKASSEFDRVALYTKYPILGVPFTVKESCGLKGLSFAVGSLAR--KNMKAPQDGDVVELVRAAG 162
                  :.:|.|:..  |:.|:|.::|:.|.::|:..::|.|.|  |.....::..:|..:|..|
Yeast   114 ------DSNRPAILP--PLYGIPISLKDQCNVEGVDTSLGYLCRTFKPKTKNEESLIVSFLRDLG 170

  Fly   163 GIPLLVSANPEFCMSFETSNNIQGRCLNPYDLQRTSAGSSGGEASLNGCGATTFGVGSDISGSIR 227
            .|..:.:..|...|:.:|.:|..|...|..:|..:|.||||||.||.|...:..|:|:||.||||
Yeast   171 AIIFVKTTVPSSMMATDTQSNTFGYTYNSINLSFSSGGSSGGEGSLIGAHGSLLGLGTDIGGSIR 235

  Fly   228 LPALFCGVFGHKPTGGLTSVKGHFPYSLTDKKFS--EMLQ--IGPITRFARDLPLLLEIMAGDKK 288
            :|:.:.|:||.|||      .|..||...|..|.  |.:.  |||:.|...||...:..:
Yeast   236 IPSSYQGLFGLKPT------FGRVPYLRVDNSFEGRETIPSVIGPLARDLSDLRYFMSCV----- 289

  Fly   289 HKLKMSEPVALKDMK-VYYAFGYSGFNCLTHPVVDF---DIKLAITKAVTCLERGGVQSKKLDLK 349
              :.:.:| .::|:| :.|.|..|......:.||..   |              |.:.....|::
Yeast   290 --INICQP-WVQDVKCIPYHFDSSTSKLHDNYVVGIWYGD--------------GVIDPPPSDIR 337

  Fly   350 FLRNSLEIALVSLVDL----KGLPSIVTQRADRDPSMRLLMVELFNSIIGHSIFTKEAMVLEVMK 410
                    ||.:..||    ||:.::     ..:||..|.. |||:       ...||.|.:
Yeast   338 --------ALKTCEDLVNKTKGMKAV-----KWEPSSELSR-ELFD-------LANEADVAD--- 378

  Fly   411 RFNGLMATGN--MEEYRVEAQKIKSHLNQLLGTQG------------------------------ 443
                   :||  ..|:.:..:.:...|..::...|
Yeast   379 -------SGNEIKNEFEISGEPLLDILKPMVLENGRPPYTVNEWWDLTKRVYNAQQLMRDYYLSF 436

  Fly   444 -------VLIMPTFHTSALCFHTSLLNVTGIDNLLLFNILGLPATHVPMGT-------------- 487
                   |:|.|   |:.:.|....:..|.:..:||||:|..|:..:|:|:
Yeast   437 PESERPDVIISP---TTLMPFRPGDMLKTTLRYILLFNVLNFPSLSIPVGSVDCQIDGLMDTTSA 498

  Fly   488 -NQR------------------GMPIGLQVVAAQYQDKLCLKVAAEL 515
             |..                  |.|||||||:..:.|....|.|:.|
Yeast   499 LNPEDKMIKTYWNDLIQSGEIDGFPIGLQVVSPTFNDNEVCKFASWL 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7910	NP_001287222.1	GatA	41..527	CDD:223232	132/561 (24%)
		PRK07488	41..525	CDD:236030	132/561 (24%)
AMD2	NP_010528.3	Amidase	79..539	CDD:396144	126/532 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I1462
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I1370
Isobase	1	0.950	-	0.69812	Normalized mean entropy	S4795
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46650
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1914
SonicParanoid	1	1.000	-	-		X256
TreeFam	0	0.000	Not matched by this tool.
	8	7.840