DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7910 and faah2b

DIOPT Version :9

Sequence 1:	NP_001287222.1	Gene:	CG7910 / 40956	FlyBaseID:	FBgn0037547	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001070930.1	Gene:	faah2b / 768298	ZFINID:	ZDB-GENE-061027-358	Length:	526	Species:	Danio rerio

Alignment Length:	507	Identity:	199/507 - (39%)
Similarity:	285/507 - (56%)	Gaps:	27/507 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QKPK-FSGIRNPLLKKSVVELVTQLRRGEITSVELVSAYIARVQEVNPSLNAVVEDRFEAALQDA 93
            ::|| ...|.||||..|.|:|..::||||::|||:|.|||.|:|||||.|||:::|||.|||.:|
Zfish    33 KRPKHLPPITNPLLTLSAVQLAEKIRRGEVSSVEVVQAYIDRIQEVNPLLNALIKDRFSAALLEA 97

  Fly    94 KLADQFIEKASSEFDRVALYTKYPILGVPFTVKESCGLKGLSFAVGSLARKNMKAPQDGDVVELV 158
            ..||:.|::.:.  ....|..::|:||||.:||||.||:|:..:.|..:|..:.|..|...|.|:
Zfish    98 ARADKLIKEENG--GEEVLRNQFPLLGVPMSVKESFGLQGMPNSGGLKSRGKVLASVDAPPVALL 160

  Fly   159 RAAGGIPLLVSANPEFCMSFETSNNIQGRCLNPYDLQRTSAGSSGGEASLNGCGATTFGVGSDIS 223
            :.||.|||.|:...|.||..|::|::.|...|||:|:|...||||||.|:.|.||:.||:||||.
Zfish   161 KRAGAIPLGVTNTSELCMWMESNNHLYGITSNPYNLERICGGSSGGEGSIIGGGASVFGIGSDIG 225

  Fly   224 GSIRLPALFCGVFGHKPTGGLTSVKGHFPYSLTDKKFSEMLQIGPITRFARDLPLLLEIMAGDKK 288
            ||||:|..|.|:|||||:.|:.|....||  ......:|....||:.|:|.||..||:||||...
Zfish   226 GSIRMPCFFNGIFGHKPSRGVVSNDNQFP--RCSGLQNEYTGSGPMCRYAEDLLPLLKIMAGPTA 288

  Fly   289 HKLKMSEPVALKDMKVYYAFGYSGFNCLTHPVVDFDIKLA-ITKAVTC-LERG-GVQSKKLDLKF 350
            .||.:|:.|.||.:: ::.....|.:.||.||   |.:|. :.|.|.. ||.. ||..::::...
Zfish   289 DKLTLSKAVDLKKLR-FFTIVDDGGSPLTSPV---DRQLVEVQKRVAARLEADLGVTVQEVNFPQ 349

  Fly   351 LRNSLEI--ALVSLVDLKGLPSIVTQRADRDPSMRLLMVELFNSIIGHSIFTKEAMVLEVMKRFN 413
            |:.|.:|  ..::|.|..|.|.........|......:.||...|.|.|..|..|:.|.:|:..:
Zfish   350 LKYSYQIWDTFLALPDKDGKPPEAFVELMADGGSVWPVWELIKRIFGRSEHTVAAIGLALMESSH 414

  Fly   414 GLMATGNMEEYRVEAQKIKSHLNQLLGTQGVLIMPTFHTSALCFHTSL-----LNVTGIDNLLLF 473
               ::.:.|....:.:.::..:..||||.|||:.|:....|...|..|     .:.|||     .
Zfish   415 ---SSKSSEFILKQKEDLQREMEDLLGTDGVLLYPSHPLLAPKHHHPLFMPFNFSYTGI-----L 471

  Fly   474 NILGLPATHVPMGTNQRGMPIGLQVVAAQYQDKLCLKVAAELEAVFHGWVPP 525
            ||||||.|..|:|.::..:|:|:||||...||.|.|.:|..||..|.|||.|
Zfish   472 NILGLPVTQCPLGLSKERLPLGVQVVAGLCQDHLTLAMALYLEKAFGGWVDP 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7910	NP_001287222.1	GatA	41..527	CDD:223232	194/495 (39%)
CG7910	NP_001287222.1	PRK07488	41..525	CDD:236030	193/493 (39%)
faah2b	NP_001070930.1	PRK07488	45..518	CDD:236030	189/488 (39%)
faah2b	NP_001070930.1	GatA	48..523	CDD:223232	191/490 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D852596at2759
OrthoFinder	1	1.000	-	-		FOG0002245
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43372
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.880