DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7910 and faah2a

DIOPT Version :9

Sequence 1:	NP_001287222.1	Gene:	CG7910 / 40956	FlyBaseID:	FBgn0037547	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_001002700.1	Gene:	faah2a / 436973	ZFINID:	ZDB-GENE-040718-453	Length:	532	Species:	Danio rerio

Alignment Length:	527	Identity:	188/527 - (35%)
Similarity:	289/527 - (54%)	Gaps:	16/527 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RLLAFILNAFGMLVNKILDFVLPRQK---PKFSGIRNPLLKKSVVELVTQLRRGEITSVELVSAY 67
            |.|..:|.|...::........|:|:   .:...|.||||..|.::|..::||.|:||||:|.||
Zfish     8 RFLGRLLRAVVWILFAAFKLFAPQQRHGVSRLPPITNPLLLLSAMQLARKIRRKEVTSVEVVQAY 72

  Fly    68 IARVQEVNPSLNAVVEDRFEAALQDAKLADQFIEKASSEFDRVALYTKYPILGVPFTVKESCGLK 132
            |.|:|||||.:||:|:|||.||||:|...|:.||:.:...|  .|..:.|:||||.||||:..|:
Zfish    73 IDRIQEVNPLINAMVKDRFSAALQEAAQVDKLIEEETGGED--VLEDRLPLLGVPITVKEAFALQ 135

  Fly   133 GLSFAVGSLARKNMKAPQDGDVVELVRAAGGIPLLVSANPEFCMSFETSNNIQGRCLNPYDLQRT 197
            |:..:.|.|.|:::.:..|...|.|::.||.|||.|:...|.||..|:.|::.|...||||.:|.
Zfish   136 GMPNSTGLLTRRDLVSGADAPSVALLKRAGAIPLGVTNCSELCMWLESHNHLYGITNNPYDFERI 200

  Fly   198 SAGSSGGEASLNGCGATTFGVGSDISGSIRLPALFCGVFGHKPTGGLTSVKGHFPYSLTDKKFSE 262
            ..||||||.|:.|.|::..|:||||.||||:|..|.|:|||||:.|:.:.:|.:|.:...:  ..
Zfish   201 VGGSSGGEGSILGAGSSVIGIGSDIGGSIRIPCFFNGIFGHKPSVGIVNNEGQYPPASGQQ--MG 263

  Fly   263 MLQIGPITRFARDLPLLLEIMAGDKKHKLKMSEPVALKDMKVYYAFGYSGFNCLTHPVVDFDIKL 327
            .|..||:.|:|.||..:|.||.|....||.:...|.||.:: :::..::|.:.|..| |:..:..
Zfish   264 FLCTGPMCRYAEDLIPMLSIMGGPNAEKLSLFTEVDLKKLR-FFSVPHNGGSHLVSP-VEPQLLH 326

  Fly   328 AITKAVTCLERG-GVQSKKLDLKFLRNSLEI--ALVSLVDLKGLPSIVTQRADRDPSMRLLMV-E 388
            |....|..||.. ||:.::|.:..|:.|.:|  .:::.....|.|.........:...::... |
Zfish   327 AQKMVVKRLEADLGVKVQELLIPQLKYSFQIWGTMMASPGKDGKPPTTFAELMSEGGKKVWPAWE 391

  Fly   389 LFNSIIGHSIFTKEAMVLEVMKRFNGLMATGNMEEYRVEAQKIKSHLNQLLGTQGVLIMPTFHTS 453
            ||...:|.|..|..|:.|.:::.|.....:..:.:   :.:.::..|.:||||.|||:.|:....
Zfish   392 LFKWFLGFSSHTLAAIGLALVELFQSSHPSPFIMQ---QKESLQQELEELLGTDGVLLYPSHPLI 453

  Fly   454 ALCFHTSLLNVTGIDNLLLFNILGLPATHVPMGTNQRGMPIGLQVVAAQYQDKLCLKVAAELEAV 518
            |...|..:..........:|||||||.|..|:|.:..|:|:|:|:||.:.||:|.|..|..||..
Zfish   454 AQKHHHPIFTPFNFSYTGIFNILGLPVTQCPLGLSAEGLPLGVQIVAGKLQDRLSLATALYLEKA 518

  Fly   519 FHGWVPP 525
            |.||..|
Zfish   519 FGGWREP 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7910	NP_001287222.1	GatA	41..527	CDD:223232	179/489 (37%)
CG7910	NP_001287222.1	PRK07488	41..525	CDD:236030	178/487 (37%)
faah2a	NP_001002700.1	PRK07488	46..526	CDD:236030	179/489 (37%)
faah2a	NP_001002700.1	Amidase	48..525	CDD:302749	176/485 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D852596at2759
OrthoFinder	1	1.000	-	-		FOG0002245
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43372
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.880