DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7910 and Faahl

DIOPT Version :9

Sequence 1:	NP_001287222.1	Gene:	CG7910 / 40956	FlyBaseID:	FBgn0037547	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_077046.1	Gene:	Faahl / 29347	RGDID:	6491947	Length:	579	Species:	Rattus norvegicus

Alignment Length:	573	Identity:	146/573 - (25%)
Similarity:	232/573 - (40%)	Gaps:	133/573 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 RQKPKFS-----------GIRNP------LLKKSVVELVTQLRRGEITSVELVSAYIARVQEVNP 76
            |||.:.|           .::||      ||...:::||.:|:.||::...:...|:.:..|||.
  Rat    45 RQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELSPEAVFFTYLGKAWEVNK 109

  Fly    77 SLNAVVEDRFEAALQDAKLADQFIEKASSEFDRVALYTKYPILGVPFTVKESCGLKGLSFAVGSL 141
            ..|.|.          :.|.|  .|...|:..|..|     :.|||.::||....||....:|..
  Rat   110 GTNCVT----------SYLTD--CETQLSQAPRQGL-----LYGVPVSLKECFSYKGHDSTLGLS 157

  Fly   142 ARKNMKAPQDGDVVELVRAAGGIPLLVSANPEFCMSFETSNNIQGRCLNPYDLQRTSAGSSGGEA 206
            ..:.|.:..|..||::::..|.:|.:.:..|:..:||:.||.:.|:.:||:...::..||||||.
  Rat   158 LNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWKSSKSPGGSSGGEG 222

  Fly   207 SLNGCGATTFGVGSDISGSIRLPALFCGVFGHKPTGGLTSVKG--HFPYSLTDKKFSEMLQIGPI 269
            :|.|.|.:..|:|:||.||||.|:.|||:.|.||||...|..|  ...|..|    :..|.:||:
  Rat   223 ALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVYGQT----AVQLSLGPM 283

  Fly   270 TRFARDLPLLLEIMAGDKKHKLKMSEPVALKDMKVYYA-----FGYSGFNCLTHPVVDFDIKLAI 329
            .|....|.|.|:.:..:....|..:.|......:||.:     .||...:..|.|.......|..
  Rat   284 ARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGYYETDNYTMPSPAMRRALIE 348

  Fly   330 TK--------------------AVTCLERGGVQSKKLDLKFLRN----SLEIALVSLVDLKGLPS 370
            ||                    |:..|..||:.|.. ...||:|    .::..|..|:.:..|||
  Rat   349 TKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDG-GRSFLQNFKGDFVDPCLGDLILILRLPS 412

  Fly   371 IVTQRADRDPSMRLLMVELFNSIIG--HSIFTKEAMVLEVMKRFNGLMATGNMEEYRV------E 427
            ...:      .:.||:..||..:..  :|:..:.|..|..::.        .:|.||.      :
  Rat   413 WFKR------LLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQH--------EIEMYRQSVIAQWK 463

  Fly   428 AQKIKSHLNQLLGTQGVLIMPTFHTSALCFHTSLLNVTGIDNLLLFNILGLPATHVPMGT----- 487
            |..:...|..:||....|..|...|.|:.:            .:|:|.|..||..||:.|
  Rat   464 AMNLDVLLTPMLGPALDLNTPGRATGAISY------------TVLYNCLDFPAGVVPVTTVTAED 516

  Fly   488 ------------------------NQRGMPIGLQVVAAQYQDKLCLKVAAELE 516
                                    |..|:|:.:|.||..:|::|||:...|:|
  Rat   517 DAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVE 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7910	NP_001287222.1	GatA	41..527	CDD:223232	140/544 (26%)
CG7910	NP_001287222.1	PRK07488	41..525	CDD:236030	140/544 (26%)
Faahl	NP_077046.1	Amidase	95..562	CDD:418511	129/514 (25%)
Faahl	NP_077046.1	Substrate binding	238..241		1/2 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336609
Domainoid	1	1.000	110	1.000	Domainoid score	I6159
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4439
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D438196at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44893
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.800