DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7910 and faah-4

DIOPT Version :9

Sequence 1:	NP_001287222.1	Gene:	CG7910 / 40956	FlyBaseID:	FBgn0037547	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_499545.1	Gene:	faah-4 / 176620	WormBaseID:	WBGene00013232	Length:	647	Species:	Caenorhabditis elegans

Alignment Length:	576	Identity:	148/576 - (25%)
Similarity:	238/576 - (41%)	Gaps:	147/576 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 NPLLKKSVVELVTQLRRGEITSVELVSAYIARVQEVNPSLNAVVEDRFEAALQDAKLADQFIEKA 103
            |.:||..::.|.:.|:..:..:..::.|::.|..:||..:|.:.|...||......|.|.:.:..
Worm    88 NEILKLDLIALKSALQTDKYNAYTVLCAFVWRAIDVNSEINCITEVIREAFNTAEALDDNYAQTG 152

  Fly   104 SSEFDRVALYTKYPILGVPFTVKESCGLKGLSFAVGSLAR-----KNMKAPQDGDVVELVRAAGG 163
            .          |..:.|:||:||.:..::.....|| ||:     |....|    :|:.:...|.
Worm   153 E----------KGQLFGLPFSVKSNFYMENYDVTVG-LAKLLEQPKTTTCP----MVQFLSDQGA 202

  Fly   164 IPLLVSANPEFCMSFETSNNIQGRCLNPYDLQRTSAGSSGGEASLNGCGATTFGVGSDISGSIRL 228
            :|..::..|:..:|:.:||.|.|...||:|..||..|||||||:|...|...||:|||::||:|:
Worm   203 VPFCLTNVPQGLLSYVSSNPIYGTTKNPWDFSRTPGGSSGGEAALLAAGGAAFGIGSDLAGSLRI 267

  Fly   229 PALFCGVFGHKPT----------GGLTSVKGHFPYSLTDKKFSEMLQIGPITRFARDLPLLLEIM 283
            ||.|||:...|||          |||.. :|...           |..|..||..::...||.::
Worm   268 PAAFCGLVTLKPTQDRLCVTDTHGGLPG-RGRLG-----------LSFGFYTRSVKEQEFLLGLI 320

  Fly   284 AGDKKH--KLKMSEPVAL-----KDMKVYYA-FGYSGFNCLTHPVVDFDIKLAITKAVTCLERGG 340
            .|..::  ...||.|..|     ||.|:... |...|||    |||..: :.|:.:.|..|:..|
Worm   321 VGRSEYLELCPMSSPAKLEKHIEKDQKLVIGWFVDDGFN----PVVPSN-RRAVEETVKSLQAKG 380

  Fly   341 VQSKKLDLKFLRNSLEIALVSLVDL---KGLPS--------IVTQRADRDPSMRLLMVELFNSII 394
            .|  .::||....|.|....::.|:   ..:|.        ...::.|....:.:.:|.|..:.:
Worm   381 HQ--VVELKLADVSEEFPPFAVADMLFRNVMPDNGAYMSEMYAGEQYDEHMKLFIRLVCLKQNFL 443

  Fly   395 -------GHSIFTKEAMVLEVMKR-------FNGLMAT-----GNMEEYRVE------AQKIKSH 434
                   |...|.|    |.:.||       :|..:|.     .|.:.|:::      ::||.:
Worm   444 VSFLLRYGVMPFAK----LALSKRLACIGSAYNSDLAACRQNQENTDSYKLQWIRYWKSKKIDA- 503

  Fly   435 LNQLLGTQGVLIMPTFHTSALCFH--TSLLN---VTGIDNLLLFNILGLPATHVPMG-TNQR--- 490
                      ||.|:|.|.|..|.  ..|.|   :||     |||:|.:||..||:. .||:
Worm   504 ----------LICPSFITPAQPFEYPAQLSNGAFITG-----LFNMLDVPAGVVPVSPVNQKDVD 553

  Fly   491 -------------------------GMPIGLQVVAAQYQDKLCLKVAAELEAVFHG 521
                                     |:|..:|||.....:::||:|...:|....|
Worm   554 QLIDGFSTEGDLLLKKQREAARGTTGLPNAVQVVTLPNCEEMCLRVMRLVEESAEG 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7910	NP_001287222.1	GatA	41..527	CDD:223232	147/574 (26%)
CG7910	NP_001287222.1	PRK07488	41..525	CDD:236030	147/574 (26%)
faah-4	NP_499545.1	Amidase	112..597	CDD:418511	138/538 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157407
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D438196at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850