Protein Alignment mAChR-B and chrm1b

DIOPT Version :9

• Sequence 1: NP_649764.1
• Gene: mAChR-B / 40955
• FlyBaseID: FBgn0037546
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: XP_001334664.4
• Gene: chrm1b / 794658
• ZFINID: ZDB-GENE-070705-188
• Length: 487
• Species: Danio rerio
• Alignment Length: 886
• Identity: 156/886 - (17%)
• Similarity: 259/886 - (29%)
• Gaps: 455/886 - (51%)

  Fly   131 WQTILIAICLAICIILTVGGNILVLLAFIVDRNIRQPSNYFIASLAATDMLIGTVSMPFYTIYVL 195
            |:.:||.:......::|:.||.||:::..|:..:|..|||::.|||..|:::|||||..||.||:
Zfish    23 WEVVLIVLVTGPLSLITILGNSLVVISIRVNSQLRTISNYYLLSLAVADLILGTVSMNLYTAYVI 87

  Fly   196 KGYWDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMVTITWII 260
            .|.|.|||:.|||||::||.|...|...:|:|:.|||.||.....||:.||......::.:.|:|
Zfish    88 LGRWTLGPLACDLWLTLDYVVSNASVMNLLVISFDRYFSVTRPLTYRTKRTPKTAAVLIALAWVI 152

  Fly   261 PALLFFISIFGWEHFTGKRDLLPGQ-CAVQFLKDPIFNTALIIGYYWTTLIVLFVLYAGIYKTAY 324
            ..:|:..:|..|.|..|:....... |::.|||.|.......|..::..:.::.:||..||   :
Zfish   153 SFILWGPAILFWPHVMGRPSGAEAHVCSIPFLKVPPITYGTAIAAFYLPVSIMIILYWRIY---W 214

  Fly   325 DMQKRSEAKQRKMQSMVALSAGAMSGMAGHAAGIGVIEEKILKTKVELAGDQTDLDSACTTVIKR 389
            :::.|::                  |:||.   :|.::.
Zfish   215 EIENRAK------------------GLAGF---VGSVKN-------------------------- 232

  Fly   390 LSGSGQANPLAVATEEVEKMTPEQRRASAAKIQEEAKKREAAVDAEKSERSSSPAFDSDEESSVN 454
                        |||.:|                                    .||
Zfish   233 ------------ATEILE------------------------------------GFD-------- 241

  Fly   455 QAQQLITQQKLNNMRKRSSIGLVFGAQAALLATRGKGNLQKSTTNSKSIEAMHQYHHHQQHHHNQ 519
                   :|.::....:|::.:    ....::.:|:|
Zfish   242 -------KQSMHQTSSKSTLSI----SREGISKKGQG---------------------------- 267

  Fly   520 SPLQRAQSKEEMRSLHHHQNQQQPHHQHHQNQPNPPLDRPKRTSCST---LSQIAEHDRLVDLSA 581
                                                    |...|.|   .::.|.|
Zfish   268 ----------------------------------------KSVGCFTWILRNKTAAH-------- 284

  Fly   582 PPTLLNTSDPLSPVDLAPIEVPSDQVHQGLVQTILPPPDAFQCPTPLSDDYSDRPFGNSSGNSEL 646
                                                            :.|.: |:.:||.|:|
Zfish   285 ------------------------------------------------ESYKE-PYSSSSWNTE- 299

  Fly   647 ALTYDLMTNSELRYMDESSAMLASVTANSTTSPNDSVQGKPPVLPPPPPARRNPPKSNLNQSLSQ 711
                           |...::|:|.| :....||:.:                           :
Zfish   300 ---------------DVDDSVLSSST-DEEHEPNNKL---------------------------K 321

  Fly   712 TPSQNQSPSQSLSLNLNPNHNQSQSQSIEEAVAIEKRLLVSYTGIEDFAKVRRESCIEAICLLDV 776
            .||.|.|     ::.|...|.:|....                |:::
Zfish   322 APSSNPS-----AIKLKDLHCRSDDTK----------------GVQE------------------ 347

  Fly   777 PGKLAADCPHRRASSPMETSSKDAILYSPMPPMPLSPKVKTSTPQTGTPQSAAGVTPPVPLERIE 841
                        .:||.|..:|..         .|.||
Zfish   348 ------------QNSPAERLTKQC---------HLKPK--------------------------- 364

  Fly   842 ERETSDSNTNKMPSTSGTTSSTGGVGGGGEQDGVGATKKNAGDDDANREEKSLAASRNSSKRAFI 906
               .||
Zfish   365 ---KSD----------------------------------------------------------- 367

  Fly   907 HSIGKHFKSKKALPLILGVGGRQKSKSENRARKAFRTISFILGCFVACWTPYHVLALVEGFCRHP 971
            |||.:..::|..:.||:            :.:||.||:|.||..|:..||||:::.|..    ..
Zfish   368 HSIRQQLRAKHRIILII------------KEKKAARTLSAILLAFILTWTPYNIMVLAS----IS 416

  Fly   972 PCINEHLYMFSYFLCYANSPMNPFCYALANQQFKKTFTRIL 1012
            .|:.|.|:...|:|||.||.:||.||||.|:.|:.||..:|
Zfish   417 YCVPEKLWQLGYWLCYVNSTVNPMCYALCNESFRVTFKSLL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-B	NP_649764.1	7tm_1	150..>341	CDD:278431	65/191 (34%)
		7tm_4	150..>336	CDD:304433	65/186 (35%)
chrm1b	XP_001334664.4	7tm_4	37..>162	CDD:304433	51/124 (41%)
		7tm_1	42..>224	CDD:278431	66/202 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1245472at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010