Protein Alignment mAChR-B and hrh1

DIOPT Version :9

• Sequence 1: NP_649764.1
• Gene: mAChR-B / 40955
• FlyBaseID: FBgn0037546
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001036196.1
• Gene: hrh1 / 735302
• ZFINID: ZDB-GENE-070531-3
• Length: 534
• Species: Danio rerio
• Alignment Length: 920
• Identity: 165/920 - (17%)
• Similarity: 272/920 - (29%)
• Gaps: 416/920 - (45%)

  Fly   109 STMSGSSS------DSEILGPVLPPFALWQTILIAICLAICIILTVGGNILVLLAFIVDRNIRQP 167
            :|::.::|      ::.:|.|..|........::.|.|.:..:|||..|:|||.|...:|.:...
Zfish    21 TTLTTANSQFKRIDNTTLLIPSAPLHHHINNAVLGIFLGMLSLLTVIMNLLVLFAVRKERTLHTV 85

  Fly   168 SNYFIASLAATDMLIGTVSMPFYTIYVLKGYWDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRY 232
            .|.:|.||:..|:::|...||...:|:|:..|.||.::|..||.:||.....|.:::.::.:|||
Zfish    86 GNLYIVSLSIADLIVGATVMPLNLVYLLEDQWKLGHVVCQFWLVMDYVASTASIFSLFILCLDRY 150

  Fly   233 CSVKIAAKYRSWRTRTRVIYMVTITWIIPALLFFISIFGWEHFTG--KRDLLPGQCAVQFLKDPI 295
            .||:...:|..:|||.|...::...|:: ::.:.|.|.||..|..  |:..|..||...|.....
Zfish   151 RSVRHPLQYLKYRTRGRATLLICSAWLL-SMTWTIPILGWRMFASVDKKTELENQCDTDFRFVTW 214

  Fly   296 FNTALIIGYYWTTLIVLFVLYAGIYKTAYDMQKRSEAKQRKMQSMVALSAGAMSGMAGHAAGIGV 360
            |.....|..::....::.|.|:.|:....|..:..|                  ..||.|
Zfish   215 FKVLTAILNFYIPSFLMLVFYSQIFIAVRDHYREWE------------------NFAGPA----- 256

  Fly   361 IEEKILKTKVELAGDQTDLDSACTTVIKRLSGSGQANPLAVATEEVEKMTPEQRRASAAKIQEEA 425
                 |||      |.||      |:...|.                           .:|.:.:
Zfish   257 -----LKT------DATD------TLTNGLQ---------------------------LQITKAS 277

  Fly   426 KKREAAVDAEKSERSSSPAFDSDEESSVNQAQQLITQQKLNNMRKRSSIGLVFGAQAALLATRGK 490
            :|...|::|                  .:|.:.|:.|..|
Zfish   278 EKESLALNA------------------YSQNEGLLDQYSL------------------------- 299

  Fly   491 GNLQKSTTNSKSIEAMHQYHHHQQHHHNQSPLQRAQSKEEMRSLHHHQNQQQPHHQHHQNQPNPP 555
                                        :.|....::.|||.|
Zfish   300 ----------------------------EQPYNSRENTEEMTS---------------------- 314

  Fly   556 LDRPKRTSCSTLSQIAEHDRLVDLSAPPTLLNTSDPLSPVDLAPIEVPSDQVHQGLVQTILPPPD 620
              .|||..|.....|....:.:..|.|
Zfish   315 --EPKRKMCYKKKAIFNLSKRMRKSVP-------------------------------------- 339

  Fly   621 AFQCPTPLSDDYSDRPFGNSSGNSELALTYDLMTNSELRYMDESSAMLASVTANSTTSPNDSVQG 685
                                              :||:.:..:....:|              :|
Zfish   340 ----------------------------------DSEISFQSDDGETVA--------------EG 356

  Fly   686 KPPVLPPPPPARRNPPKSNLNQSLSQTPSQNQSPSQSLSLNLNPNHNQSQSQSIEEAVAIEKRLL 750
            :|                                  ||||....:.|.:|.|
Zfish   357 RP----------------------------------SLSLAFLQSENTAQPQ------------- 374

  Fly   751 VSYTGIEDFAKVRRESCIEAICLLDVPGKLAADCPHRRASSP-METSSKDAILYSPMPPMPLSPK 814
             ::..:.|             |.:.||..:...|    .|:| ::..:..|:|.:  ||.|.||.
Zfish   375 -TFINVSD-------------CNVLVPNSVGNIC----ESAPTVDIHNYTAVLCT--PPSPPSPW 419

  Fly   815 VKTSTPQTGTPQSAAGVTPPVPLERIEERETSDSNTNKMPSTSGTTSSTGGVGGGGEQDGVGATK 879
            .:.|.|..      |.:..|
Zfish   420 AENSPPLD------ASIALP--------------------------------------------- 433

  Fly   880 KNAGDDDANREEKSLAASRNSSKRAFIHSIGKHFKSKKALPLILGVGGRQKSKSENRARKAFRTI 944
                   |.:..:.|......|    |||:                    :.:.|   |||.|.:
Zfish   434 -------AKQSWQKLCEQSKQS----IHSM--------------------RIRKE---RKAARQL 464

  Fly   945 SFILGCFVACWTPYHVLALVEGFCRHPPCINEHLYMFSYFLCYANSPMNPFCYALANQQFKKTFT 1009
            .||:|.|:.||.||.:..:|...|.  .|::..|:||:.:|.|.||.:|||.|.|.|:.||:.|.
Zfish   465 GFIIGVFMVCWIPYFITFMVMALCE--TCVHHDLHMFTIWLGYINSTLNPFIYPLCNENFKRVFK 527

  Fly  1010 RILKGDLHMT 1019
            :|    .||:
Zfish   528 KI----FHMS 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-B	NP_649764.1	7tm_1	150..>341	CDD:278431	53/192 (28%)
		7tm_4	150..>336	CDD:304433	53/187 (28%)
hrh1	NP_001036196.1	7tm_4	63..>242	CDD:304433	54/179 (30%)
		7tm_1	69..>249	CDD:278431	52/180 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1245472at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010