Protein Alignment mAChR-B and chrm5b

DIOPT Version :9

• Sequence 1: NP_649764.1
• Gene: mAChR-B / 40955
• FlyBaseID: FBgn0037546
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001025331.1
• Gene: chrm5b / 561491
• ZFINID: ZDB-GENE-041001-169
• Length: 457
• Species: Danio rerio
• Alignment Length: 861
• Identity: 164/861 - (19%)
• Similarity: 245/861 - (28%)
• Gaps: 427/861 - (49%)

  Fly   155 LLAFIVDRNIRQPSNYFIASLAATDMLIGTVSMPFYTIYVLKGYWDLGPMLCDLWLSVDYTVCLV 219
            :|:|.|:..::..:||::.|||..|::||..||..||.|:|.|||.||...|||||::||.....
Zfish     1 MLSFKVNSQLKTVNNYYLLSLAFADLIIGVFSMNLYTCYILMGYWSLGNTACDLWLALDYVASNA 65

  Fly   220 SQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMVTITWIIPALLFFISIFGWEHFTGKRDLLPG 284
            |...:|:|:.|||.|:.....||:.||..|...|:.:.|:|..:|:...|..|::|.|:|.:...
Zfish    66 SVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGMAWLISFILWAPPILCWQYFVGERKVPLD 130

  Fly   285 QCAVQFLKDPIFNTALIIGYYWTTLIVLFVLYAGIYKTAYDMQKRSEAKQRKMQSMVALSAGAMS 349
            ||.:||..:||......|..::..:.::.:||..|||..
Zfish   131 QCQIQFFSEPIITFGTAIAAFYVPVSIMTILYCKIYKET-------------------------- 169

  Fly   350 GMAGHAAGIGVIEEKILKTKVELAGDQTDLDSACTTVIKRLSGSGQANPLAVATEEVEKMTPEQR 414
                         ||..|...||.|
Zfish   170 -------------EKRTKNLAELQG---------------------------------------- 181

  Fly   415 RASAAKIQEEAKKREAAVDAEKSERSSSPAFDSDEESSVNQAQQLITQQKLNNMRKRSSIGLVFG 479
                                       .|:.||.:...|.  :.::......|.|.        |
Zfish   182 ---------------------------YPSLDSQDGPKVR--KPILRCFSFKNKRD--------G 209

  Fly   480 AQAALLATRGKGNLQKSTTNSKSIEAMHQYHHHQQHHHNQSPLQRAQSKEEMRSLHHHQNQQQPH 544
            .||:..::                              |||.:.|
Zfish   210 TQASWSSS------------------------------NQSYVTR-------------------- 224

  Fly   545 HQHHQNQPNPPLDRPKRTSCSTLSQIAEHDRLVDLSAPPTLLNTSDPLSPVDLAPIEVPSDQVHQ 609
                                                                             
Zfish   225 ----------------------------------------------------------------- 224

  Fly   610 GLVQTILPPPDAFQCPTPLSDDYSDRPFGNSSGNSELALTYDLMTNSELRYMDESSAMLASVTAN 674
                            |.|..|                   ||.|.||           ...|.|
Zfish   225 ----------------TTLQSD-------------------DLWTKSE-----------QVTTLN 243

  Fly   675 STTSPNDSVQGKPPVLPPPPPARRNPPKSNLNQSLSQTPSQNQSPSQSLSLNLNPNHNQSQSQSI 739
            |.||..|.                   ..::::|..:...:||.|         |.....|
Zfish   244 SYTSSEDD-------------------DRSVSESTPRESFKNQEP---------PVSKNGQ---- 276

  Fly   740 EEAVAIEKRLLVSYTG---IEDFAKVRRESCIEAICLLDVPGKLAADCPHRRASSPMETSSKDAI 801
                      ||.|..   :.|.||                      |        .:|::|..:
Zfish   277 ----------LVCYEDSKYLSDLAK----------------------C--------SQTNNKKCL 301

  Fly   802 LYSPMPPMPLSPKVKTSTPQTGTPQSAAGVTPPVPLERIEERETSDSNTNKMPSTSGTTSSTGGV 866
            .|.      ..|.:...|...|..:|          ||....::||..     :.|.|:|||
Zfish   302 SYK------FKPIISDITVLQGNSES----------ERANPDQSSDQQ-----APSSTSSST--- 342

  Fly   867 GGGGEQDGVGATKKNAGDDDANREEKSLAASRNSSKRAFIHSIGKHFKSKKALPLILGVGGRQKS 931
                                 ..|:.:|.......||               :.||
Zfish   343 ---------------------KPEDPNLKIQMTKRKR---------------MVLI--------- 362

  Fly   932 KSENRARKAFRTISFILGCFVACWTPYHVLALVEGFCRHPPCINEHLYMFSYFLCYANSPMNPFC 996
                :.:||.:|:|.||..|:..||||:::.|:..||.:  ||...|:...|:|||.||.:||.|
Zfish   363 ----KEKKAAQTLSAILLAFLLTWTPYNIMVLISTFCSN--CIPTSLWQLGYWLCYVNSTVNPMC 421

  Fly   997 YALANQQFKKTFTRIL 1012
            |||.|:.|:|||..::
Zfish   422 YALCNKTFQKTFWMLI 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-B	NP_649764.1	7tm_1	150..>341	CDD:278431	62/185 (34%)
		7tm_4	150..>336	CDD:304433	62/180 (34%)
chrm5b	NP_001025331.1	7tm_1	1..>174	CDD:278431	64/211 (30%)
		7tm_4	16..>116	CDD:304433	41/99 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1245472at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920