DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mAChR-B and DopEcR

DIOPT Version :9

Sequence 1:	NP_649764.1	Gene:	mAChR-B / 40955	FlyBaseID:	FBgn0037546	Length:	1019	Species:	Drosophila melanogaster
Sequence 2:	NP_001014559.1	Gene:	DopEcR / 38539	FlyBaseID:	FBgn0035538	Length:	322	Species:	Drosophila melanogaster

Alignment Length:	147	Identity:	49/147 - (33%)
Similarity:	82/147 - (55%)	Gaps:	10/147 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 ALWQTILIAICLAICIILTVGGNILVLLAFIVDRNIRQPS---NYFIASLAATDMLIGTVSMPFY 190
            ||.:.:||:| |.:.|:|:   |:|::..:   .|.:.|:   ||::.|||..|:|.|.:.:||.
  Fly    15 ALTKAVLISI-LGVAIVLS---NLLIIATY---ANFKGPTEVINYYLLSLAIADLLCGLLVVPFS 72

  Fly   191 TIYVLKGYWDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMVT 255
            ....|.|.|..|.::|.....::.|:..||.||.:.|::|||.:|:...:|.:.:|:||....:.
  Fly    73 VYPALTGEWMYGDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLRYETVQTKTRCQCWMV 137

  Fly   256 ITWIIPALLFFISIFGW 272
            .|||..|||....|.|:
  Fly   138 FTWISAALLCCPPILGY 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-B	NP_649764.1	7tm_1	150..>341	CDD:278431	41/126 (33%)
mAChR-B	NP_649764.1	7tm_4	150..>336	CDD:304433	41/126 (33%)
DopEcR	NP_001014559.1	7tm_classA_rhodopsin-like	18..289	CDD:410626	47/144 (33%)
		TM helix 1	18..42	CDD:410626	8/30 (27%)
		TM helix 2	51..73	CDD:410626	10/21 (48%)
		TM helix 3	89..111	CDD:410626	6/21 (29%)
		TM helix 4	134..150	CDD:410626	6/15 (40%)
		TM helix 5	174..197	CDD:410626
		TM helix 6	230..252	CDD:410626
		TM helix 7	264..289	CDD:410626
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460669
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930