Protein Alignment mAChR-B and CG13579

DIOPT Version :10

• Sequence 1: NP_649764.1
• Gene: mAChR-B / 40955
• FlyBaseID: FBgn0037546
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Alignment Length: 717
• Identity: 130/717 - (18%)
• Similarity: 214/717 - (29%)
• Gaps: 266/717 - (37%)

  Fly    90 DVNNTNLLL--AVRNQSSDGGSTMSGSSSDSEILGPVLPPFALWQTILIAICLAICIILTVGGNI 152
            |:...:||:  ||:| ||......||.:..:.|        .:.:|| .|:.:.:..:..:|.|.
  Fly     2 DLKTGSLLVAPAVKN-SSCSHPRYSGHNFIAHI--------GIAETI-EAVLILVLTLGVIGANC 56

  Fly   153 LVLLAFIVDRN-----IRQPSNYFIASLAATDMLIGTVSMPFYTIYVLKGYWDLGPMLCDLWLSV 212
            ||:  |:::..     |.|...|.:.|||..|:.||.:..||..:..|...|..|.:.|.:...:
  Fly    57 LVI--FVINNRRYAAYIHQQPRYLLTSLALNDLTIGLLITPFGLMPALFHCWPYGEIFCQIQALL 119

  Fly   213 DYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMVTITWIIPALLFFISIFGWEHFTG 277
            ...:...|...::.:.:|||.......:|....::...:.::::||||...:|...:....::..
  Fly   120 RGALSQQSAVILVCMAVDRYMCALHPRRYYQHSSKKGCVAILSLTWIISLTVFGFLVLPKGYYFN 184

  Fly   278 KRDLLPGQCAVQFLKDPIFNTALIIGYYWTTLIVLFVLYAGIYKTAYDMQKRSEAKQRKMQSMVA 342
            ...|:   ....|...|.:........|:.|.:||...|
  Fly   185 NTGLM---ACEPFYSKPSYRILSTCALYFPTTMVLMYCY-------------------------- 220

  Fly   343 LSAGAMSGMAGHAAGIGVIEEKILKTKVELAGDQTDLDSACTTVIKRLSGSGQANPLAVATEEVE 407
                   |.:.|                                :.|...:....||..|...
  Fly   221 -------GSSFH--------------------------------MSRFRLNDPTMPLTAAAHH-- 244

  Fly   408 KMTPEQRRASAAKIQEEAKKREAAVDAEKSERSSSPAFDSDEESSVNQAQQLITQQKLNNMRKRS 472
               |.......|                                    ||||
  Fly   245 ---PHPHPHPTA------------------------------------AQQL------------- 257

  Fly   473 SIGLVFGAQAALLATRGKGNLQKSTTNSKSIEAMHQYHHHQQHHHNQSPLQRAQSKEEMRSLHHH 537
                                               |.|.|||||....          |.|..:|
  Fly   258 -----------------------------------QMHQHQQHHQQAG----------MHSHLYH 277

  Fly   538 QNQQQPHHQHHQNQPN---------PPL-------------DRPKRTSCSTLSQIAEHDRLVDLS 580
            .:...|.|..|.|.||         ||:             ..|..|:..|       .::|.:.
  Fly   278 GHSHHPSHPSHPNHPNHHGHPHHHGPPVMGHLSMAMSMGLAGMPNMTNKIT-------KKIVPIQ 335

  Fly   581 APPTLLNTSDPLSPVDLAPIEVPSDQVHQGLVQTI----LPP-PDAFQCPTPLSDDYSDRPFGNS 640
            ...:..:||..::.:.|..|.:.:....|.:|...    ||| .|.....|.||:...: ||...
  Fly   336 EKNSSGSTSRSMAAISLGFIVMVTPWTIQEIVTACTGSKLPPFLDFLVTWTALSNSLWN-PFMYW 399

  Fly   641 SGNSEL-ALTYDLMTNSELRYMD--ESSAMLASVTANS---TTSPNDSVQGKPPVLPPPPPARRN 699
            ..||:. .::..||.|....:.|  |..:....:.||.   ||.|          :||.||:.|
  Fly   400 LLNSDFRRMSRQLMPNKCFPHEDTPEHKSGCCHINANDFEITTLP----------IPPEPPSSR- 453

  Fly   700 PP---------------------KSNLNQSL------SQTPSQNQSPSQSLSLNLNPN-HNQSQS 736
            ||                     .|::..|:      |:|.|.::|.||.:...:... ||...:
  Fly   454 PPGGAGGGGGGPSSGGPSSGGGVASSIGGSVLGICGRSRTNSLSRSASQYIRGTMGGGVHNHQAT 518

  Fly   737 QS 738
            ::
  Fly   519 ET 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-B	NP_649764.1	7tmA_mAChR_GAR-2-like	147..>323	CDD:320429	38/180 (21%)
		TM helix 2	168..194	CDD:320429	9/25 (36%)
		TM helix 3	206..236	CDD:320429	5/29 (17%)
		TM helix 4	248..271	CDD:320429	5/22 (23%)
		TM helix 5	293..322	CDD:320429	6/28 (21%)
		7tm_GPCRs	<932..1008	CDD:475119
		TM helix 6	941..963	CDD:410628
		TM helix 7	976..1001	CDD:410628
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	38/183 (21%)
		TM helix 1	41..65	CDD:410626	6/25 (24%)
		TM helix 2	75..101	CDD:410626	9/25 (36%)
		TM helix 3	113..143	CDD:410626	5/29 (17%)
		TM helix 4	156..175	CDD:410626	5/18 (28%)
		TM helix 5	200..220	CDD:410626	4/19 (21%)
		7tm_GPCRs	<334..407	CDD:475119	17/73 (23%)
		TM helix 6	340..366	CDD:410628	5/25 (20%)
		TM helix 7	377..402	CDD:410628	7/25 (28%)