Protein Alignment mAChR-B and gar-1

DIOPT Version :9

• Sequence 1: NP_649764.1
• Gene: mAChR-B / 40955
• FlyBaseID: FBgn0037546
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001024402.1
• Gene: gar-1 / 180922
• WormBaseID: WBGene00001517
• Length: 713
• Species: Caenorhabditis elegans
• Alignment Length: 926
• Identity: 234/926 - (25%)
• Similarity: 385/926 - (41%)
• Gaps: 268/926 - (28%)

  Fly   127 PFALWQTILIAICLAICIILTVGGNILVLLAFIVDRNI-RQPSNYFIASLAATDMLIGTVSMPFY 190
            |:::...|::.|.:.:..:.|:.||.:|::|:.::||| :|.||.:|.|||.:|::||....||:
 Worm    18 PYSIPVQIVVWIIIIVLSLETIIGNAMVVMAYRIERNISKQVSNRYIVSLAISDLIIGIEGFPFF 82

  Fly   191 TIYVLKG-YWDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMV 254
            |:|||.| .|.||.:.|..||.:|||:||||..||||||.|||.||...|||..|::.|:...::
 Worm    83 TVYVLNGDRWPLGWVACQTWLFLDYTLCLVSILTVLLITADRYLSVCHTAKYLKWQSPTKTQLLI 147

  Fly   255 TITWIIPALLFFISIFGWEHFTGKRDLLPG-QCAVQFLKDPIFNTALIIGYYWTTLIVLFVLYAG 318
            .::|::||::|.|.|:||:..||:...:.| :|:..||.:|..|..:.:.||||||:.:.:||.|
 Worm   148 VMSWLLPAIIFGIMIYGWQAMTGQSTSMSGAECSAPFLSNPYVNMGMYVAYYWTTLVAMLILYKG 212

  Fly   319 IYKTAYDMQKRSEAKQRKMQSMVALSAGAMSGMAGHAAGIG-VIEEKILKTKVELAGDQTDLDSA 382
            |::.|.:::|:::||:|:..:::      :|...|...|:. :::.|..|.|.|    :...||.
 Worm   213 IHQAAKNLEKKAKAKERRHIALI------LSQRLGTQVGVSLMLQSKAEKEKAE----EAQKDSG 267

  Fly   383 CTTVIKRLSGSGQANPLAVATEEVEKMTPEQRRASAAKIQEEAKKREAAVDAEKSERSSSPAFDS 447
            .|:     :.:|.||.|                           :|....:.|.|:      |..
 Worm   268 YTS-----NQAGDANNL---------------------------RRFGFSEPETSQ------FRV 294

  Fly   448 DEESSVNQAQQLITQQKLNNMRKRSSIGLVFGAQAALLATRGKGNLQKSTTNSKSIEAMHQYHHH 512
            |..|:             ||:....|:                     :|.|.:::..:.:
 Worm   295 DPNSN-------------NNLNVEGSL---------------------NTENDQNLGVIEE---- 321

  Fly   513 QQHHHNQSPLQRAQSKEEMRSLHHHQNQQQPHHQHHQNQPNPPLDRPKRTSCSTLSQIAEHDRLV 577
                .....|.|.:|.|.                 :...|:|.....:|  ||.:.::
 Worm   322 ----ERSGFLSRRESNES-----------------YYPGPHPTAANSRR--CSEMEKV------- 356

  Fly   578 DLSAPPTLLNTSDPLSPVDLAPIEVPSDQVHQGLVQTILPPPDAFQCPTPLSDDYSDRPFGNSSG 642
                  :||:.||          .|||.:                  |.        :.:|..|.
 Worm   357 ------SLLSESD----------GVPSTR------------------PA--------KSYGRLSL 379

  Fly   643 NSELALTYDLMTNSE--------------LRYMDESSAML--ASVTANSTTSPNDSVQGKPPVLP 691
            .|..:.:..:.|..|              |...||..::|  ......:|.|.||| .....:|.
 Worm   380 RSRYSASESITTTHENDEKEVEKADSLQKLFADDELGSVLNFKEEKLKNTDSNNDS-DTTSVILQ 443

  Fly   692 PPPPARRNPPKSNLNQSLSQTPSQ----NQSPSQSLSLNLNPNHNQSQSQSIEE------AVAIE 746
            .....::|....:..:|...||.|    .|:...:..|......:..|:::||.      .|:::
 Worm   444 RSRKYKKNKRPRSSRRSEHSTPRQIAKVKQAEGTAAQLIEESVPDDDQTETIEVKRTDRWVVSMK 508

  Fly   747 KRLLVSYTGIEDFAKVRRESCIEAICLLDVPGKLAADCPHRRASSPMETSSKDAILYSPMPPMPL 811
            ||:.        .|.:||.|...               |.|.:||..:.||.:.
 Worm   509 KRIA--------RALIRRRSTTR---------------PERGSSSNSDDSSSEV----------- 539

  Fly   812 SPKVKTSTPQTGTPQSAAGVTPPVPLERIEERETSDSNTNKMPSTSGTTSSTGGVGGGGEQDGVG 876
                                       ..||:....:|..|:|..:....:.            |
 Worm   540 ---------------------------EGEEKPEVRNNGLKIPQLTVNNENR------------G 565

  Fly   877 ATKKNAGDD---DANREEKSLAASRNSSKRAFIHSIGKHFK--SKKALPLILGVGGRQKSKSENR 936
            .|....|.|   ..|:.:..|:||..|.|.:.|.::....|  |....|:.:...||:::|:|.|
 Worm   566 ETSSQPGRDRLAPPNKTDTFLSASGVSRKISTISTVITREKVISSIFAPIAVFNRGRKQTKAEKR 630

  Fly   937 ARKAFRTISFILGCFVACWTPYHVLALVEGFCRHPPCINEHLYMFSYFLCYANSPMNPFCYALAN 1001
            |.||||||:||:|.|...|:||:::|.|.|||: ..||...||..||::||.||..|||.|||||
 Worm   631 AHKAFRTITFIVGFFAILWSPYYIMATVYGFCK-GECIPSFLYTLSYYMCYLNSSGNPFAYALAN 694

  Fly  1002 QQFKKTFTRILKGDLH 1017
            :||:..|.|:.:|:.:
 Worm   695 RQFRSAFMRMFRGNFN 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-B	NP_649764.1	7tm_1	150..>341	CDD:278431	84/193 (44%)
		7tm_4	150..>336	CDD:304433	83/188 (44%)
gar-1	NP_001024402.1	7tm_4	39..>163	CDD:304433	58/123 (47%)
		7tm_1	41..>236	CDD:278431	84/200 (42%)
		7tm_4	<586..705	CDD:304433	55/119 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160056
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1245472at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14467
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24247
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.040