Protein Alignment mAChR-B and chrm3b

DIOPT Version :9

• Sequence 1: NP_649764.1
• Gene: mAChR-B / 40955
• FlyBaseID: FBgn0037546
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: XP_001919160.1
• Gene: chrm3b / 100149598
• ZFINID: ZDB-GENE-090410-5
• Length: 494
• Species: Danio rerio
• Alignment Length: 893
• Identity: 158/893 - (17%)
• Similarity: 249/893 - (27%)
• Gaps: 478/893 - (53%)

  Fly   120 ILGPVLPPFALWQTILIAICLAICIILTVGGNILVLLAFIVDRNIRQPSNYFIASLAATDMLIGT 184
            :|...|...::.|.::||:......:||:.||.||||:|.:::.::..:||::.|||..|::||.
Zfish    49 VLSDPLGGHSVLQVVMIALLCGSISLLTIIGNTLVLLSFKLNKQLKTVNNYYLLSLAFADLIIGV 113

  Fly   185 VSMPFYTIYVLKGYWDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTR 249
            :||..||.|::...|.||...|||||::||.....|...:|:|:.|||.||.....||:.||..|
Zfish   114 LSMNLYTTYIIMDQWALGNFACDLWLAIDYVASNASVMNLLVISFDRYFSVTRPLTYRAKRTTKR 178

  Fly   250 VIYMVTITWIIPALLFFISIFGWEHFTGKRDLLPGQCAVQFLKDPIFNTALIIGYYWTTLIVLFV 314
            .:.|:.:.|.|..:|:..:|..|::|.|:|.:.|.:|.:||:.:||......|..::..:.::.|
Zfish   179 AMTMIGLAWSISFILWAPAILFWQYFVGERTVEPDKCYIQFISEPITTFCTAIAAFYLPVTIMTV 243

  Fly   315 LYAGIYKTAYDMQKRSEAKQRKMQSMVALSAGAMSGMAGHAAGIGVIEEKILKTKVELAGDQTDL 379
            ||..|||   :.:.||.                                       ||||
Zfish   244 LYWRIYK---ETENRSR---------------------------------------ELAG----- 261

  Fly   380 DSACTTVIKRLSGSGQANPLAVATEEVEKMTPEQRRASAAKIQEEAKKREAAVDAEKSERSSSPA 444
                      |..||..
Zfish   262 ----------LKASGNV------------------------------------------------ 268

  Fly   445 FDSDEESSVNQAQQLITQQKLNNMRKRSSIGLVFGAQAALLATRGKGNLQKSTTNSKSIEAMHQY 509
                ||.||....|                                      |.:|:|
Zfish   269 ----EEESVVVVPQ--------------------------------------TGSSRS------- 284

  Fly   510 HHHQQHHHNQSPLQRAQSKEEMRSLHHHQNQQQPHHQHHQNQPNPPLDRPKRTSCSTLSQIAEHD 574
                                               |..::.||..|:.:.|..
Zfish   285 -----------------------------------HSSYELQPAAPMRKTKTR------------ 302

  Fly   575 RLVDLSAPPTLLNTSDPLSPVDLAPIEVPSDQVHQGLVQTILPPPDAFQCPTPLSDDYSDRPFGN 639
            ||...|......::||
Zfish   303 RLWFWSRGDVERSSSD------------------------------------------------- 318

  Fly   640 SSGNSELALTYDLMTNSELRYMDESSAMLASVTANSTTSPNDSVQGKPPVLPPPPPARRNPPKSN 704
            |..|:|.|::.|
Zfish   319 SWNNNETAISID----------------------------------------------------- 330

  Fly   705 LNQSLSQTPSQNQSPSQSLSLNLNPNHNQSQSQSIEEAVAIEKRLLVSYTGIEDFAKVRRESCIE 769
                            ||         :..:.:..|....|||:
Zfish   331 ----------------QS---------DDDEEEDAEHIYTIEKQ--------------------- 349

  Fly   770 AICLLDVPGKLAADCPHRRASSPMETSSKDAILYSPMPPMPLSPKVKTSTPQTGTPQSAAGVTPP 834
                 |:..|
Zfish   350 -----DLEAK------------------------------------------------------- 354

  Fly   835 VPLERIEERETSDSNTNKMPSTSGTTSSTGGVGGGGEQDGVGATKKNAGDDDANREEKSLAASRN 899
                               ||..|.:.|:                      ..:.:::.:.::|.
Zfish   355 -------------------PSKFGVSKSS----------------------TLDSKDQPVKSARK 378

  Fly   900 SSKRAFIHSIGKHFKSKKALPLILGVGGRQKSKSENRARKAFRTISFILGCFVACWTPYHVLALV 964
            ::||             |.|.|:             :.:||.:|:|.||..|:..||||:::.|:
Zfish   379 TNKR-------------KKLSLV-------------KEKKAAQTLSAILLAFIITWTPYNIMVLL 417

  Fly   965 EGFCRHPPCINEHLYMFSYFLCYANSPMNPFCYALANQQFKKTFTRIL 1012
            ..||  ..||.|.|:...|:|||.||.:||.||||.|:.|:.||..||
Zfish   418 NAFC--DGCIPETLWALGYWLCYVNSTVNPMCYALCNKAFRTTFRSIL 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAChR-B	NP_649764.1	7tm_1	150..>341	CDD:278431	67/190 (35%)
		7tm_4	150..>336	CDD:304433	67/185 (36%)
chrm3b	XP_001919160.1	7tm_4	72..>244	CDD:304433	61/171 (36%)
		7tm_1	79..448	CDD:278431	141/846 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1245472at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920