DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11035 and DNAJB14

DIOPT Version :9

Sequence 1:	NP_001303469.1	Gene:	CG11035 / 40953	FlyBaseID:	FBgn0037544	Length:	231	Species:	Drosophila melanogaster
Sequence 2:	NP_001026893.1	Gene:	DNAJB14 / 79982	HGNCID:	25881	Length:	379	Species:	Homo sapiens

Alignment Length:	181	Identity:	41/181 - (22%)
Similarity:	71/181 - (39%)	Gaps:	42/181 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SHYDALGIRRQCTQNEIKAAYYKLSMLYHPDRNQGSENAAKKFREINQAYEILGNYRLRRLYD-- 89
            ::|:.||:.:.....::|.||.||::.:|||:|. :..|...|::|..||.:|.|...|:.||
Human   108 NYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNH-APGATDAFKKIGNAYAVLSNPEKRKQYDLT 171

  Fly    90 ----KGIVHTAGAQYAQDVHDVAE-PVVEDDAETKFYKSRFQKSRV-SDSAGRTPIYDFDEWSRN 148
                :...|....::  :.|...| .:..:|....|:...|....| |.|.||.
Human   172 GNEEQACNHQNNGRF--NFHRGCEADITPEDLFNIFFGGGFPSGSVHSFSNGRA----------- 223

  Fly   149 HYGKSFDRRQAAQAKYDRIKVQRETNRISGQTDMVLLAFIFAGVAVYLMFL 199
            .|.:....|.:..        :||..|..|            |.:|::..:
Human   224 GYSQQHQHRHSGH--------EREEERGDG------------GFSVFIQLM 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11035	NP_001303469.1	DnaJ	26..>89	CDD:223560	20/61 (33%)
CG11035	NP_001303469.1	DnaJ	27..89	CDD:278647	20/61 (33%)
DNAJB14	NP_001026893.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..94
		DnaJ	107..>214	CDD:223560	28/108 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..241		7/40 (18%)
		DUF1977	271..371	CDD:370429
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810