DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11035 and DNAJB2

DIOPT Version :9

Sequence 1:	NP_001303469.1	Gene:	CG11035 / 40953	FlyBaseID:	FBgn0037544	Length:	231	Species:	Drosophila melanogaster
Sequence 2:	NP_006727.2	Gene:	DNAJB2 / 3300	HGNCID:	5228	Length:	324	Species:	Homo sapiens

Alignment Length:	210	Identity:	46/210 - (21%)
Similarity:	86/210 - (40%)	Gaps:	35/210 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SHYDALGIRRQCTQNEIKAAYYKLSMLYHPDRN-QGSENAAKKFREINQAYEILGNYRLRRLYDK 90
            |:|:.|.:.|..:.::||.||.:.::.:|||:| ...|.|.|||:|:.:|||:|.:...|.:||:
Human     3 SYYEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKREIYDR 67

  Fly    91 ----GIVHT--------AGAQYAQDVHDVAEPVVEDDAETKFYKSRFQKSRVSDSAGRTPIYDFD 143
                |:..|        ||:...........|   ::...:|:.|....:.:.|..|  |..:..
Human    68 YGREGLTGTGTGPSRAEAGSGGPGFTFTFRSP---EEVFREFFGSGDPFAELFDDLG--PFSELQ 127

  Fly   144 EWSRNHYGKSFDRRQAAQAKYDRIKVQRETNRISGQTDMVLLAFIFA-GVAVYLMFLAESSYDTP 207
            .....|.|..|                ..::...|.:|....:|.|: |...:......:::...
Human   128 NRGSRHSGPFF----------------TFSSSFPGHSDFSSSSFSFSPGAGAFRSVSTSTTFVQG 176

  Fly   208 KQKAKERYRRDQEER 222
            ::....|...:.:||
Human   177 RRITTRRIMENGQER 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11035	NP_001303469.1	DnaJ	26..>89	CDD:223560	23/62 (37%)
CG11035	NP_001303469.1	DnaJ	27..89	CDD:278647	23/62 (37%)
DNAJB2	NP_006727.2	DnaJ	3..>110	CDD:223560	31/109 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..90		4/19 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..324
		CAAX motif. /evidence=ECO:0000269\|PubMed:12754272	321..324
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810