DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11035 and sec63

DIOPT Version :9

Sequence 1:	NP_001303469.1	Gene:	CG11035 / 40953	FlyBaseID:	FBgn0037544	Length:	231	Species:	Drosophila melanogaster
Sequence 2:	NP_595985.1	Gene:	sec63 / 2540961	PomBaseID:	SPBC36B7.03	Length:	611	Species:	Schizosaccharomyces pombe

Alignment Length:	225	Identity:	45/225 - (20%)
Similarity:	80/225 - (35%)	Gaps:	75/225 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 YDALGIRRQCTQNEIKAAYYKLSMLYHPDR-----NQGSENAAKKFREINQAYEILGNYRLRRLY 88
            |:.|||.:..:.::::..|.:||:.:|||:     |...|...|.:.||..||..|.:.:.|..|
pombe   100 YEILGIAKGTSVDDVRRHYKRLSIKFHPDKVRNMVNTTREEVEKHYIEITNAYRALTDDKTRENY 164

  Fly    89 ------------------DKGIVHTAGAQYAQDVHDVAEPVVEDDAETK-FYKSR-FQKSRVSDS 133
                              .|.|..:..:.|....:.:...:|...|..| :|.|| :.:..|.
pombe   165 ALYGTPDVPQHISVGIALPKWISESENSIYILGFYGLVFGIVLPYAVGKWWYGSRTYTRDHVH-- 227

  Fly   134 AGRTPIYDFDEWSRNHYGKSFDRRQA-----------AQAK--------------------YDRI 167
                 :...|||        |.:.:.           |.:|                    :|.:
pombe   228 -----VDTVDEW--------FPKMETSLTLDELLSLFASSKELTSLVPNEKNPKEYILKLLFDHL 279

  Fly   168 KVQR----ETNRISGQTDMVLLAFIFAGVA 193
            ..::    .|::|..|:|:||.|.:....|
pombe   280 NRKKTNNFNTHQILSQSDVVLNALLSVATA 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11035	NP_001303469.1	DnaJ	26..>89	CDD:223560	20/82 (24%)
CG11035	NP_001303469.1	DnaJ	27..89	CDD:278647	20/82 (24%)
sec63	NP_595985.1	SEC63	1..611	CDD:227694	45/225 (20%)
		DnaJ	98..164	CDD:278647	19/63 (30%)
		Sec63	229..541	CDD:214946	15/89 (17%)
		Nro1	<543..>599	CDD:289519
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910