DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11035 and DNAJC18

DIOPT Version :9

Sequence 1:	NP_001303469.1	Gene:	CG11035 / 40953	FlyBaseID:	FBgn0037544	Length:	231	Species:	Drosophila melanogaster
Sequence 2:	NP_689899.1	Gene:	DNAJC18 / 202052	HGNCID:	28429	Length:	358	Species:	Homo sapiens

Alignment Length:	190	Identity:	44/190 - (23%)
Similarity:	76/190 - (40%)	Gaps:	38/190 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SHYDALGIRRQCTQNEIKAAYYKLSMLYHPDRNQGSENAAKKFREINQAYEILGNYRLRRLY--- 88
            ::|:.||:.|..:..|:|.||.||::.:|||:| .:..|...|:.|..|:.:|.|...|..|
Human    82 NYYEILGVSRDASDEELKKAYRKLALKFHPDKN-CAPGATDAFKAIGNAFAVLSNPDKRLRYDEY 145

  Fly    89 -DKGIVHTA-GAQYAQDVHDVAEPVVEDDAETKFYKSRFQK------SRVSDSAGRTPIYDFDEW 145
             |:.:..|| .|:......|....:..::....|:...|..      |.|:|        |...:
Human   146 GDEQVTFTAPRARPYNYYRDFEADITPEELFNVFFGGHFPTGNIHMFSNVTD--------DTYYY 202

  Fly   146 SRNHYGKSFDRRQAAQAKYDRIKVQRETNRISGQTD-----MVLLAFIFAGVAVYLMFLA 200
            .|.|             :::|.:.|:|......||.     .:|...:...::|....||
Human   203 RRRH-------------RHERTQTQKEEEEEKPQTTYSAFIQLLPVLVIVIISVITQLLA 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11035	NP_001303469.1	DnaJ	26..>89	CDD:223560	22/65 (34%)
CG11035	NP_001303469.1	DnaJ	27..89	CDD:278647	22/65 (34%)
DNAJC18	NP_689899.1	DnaJ	82..143	CDD:278647	21/61 (34%)
DNAJC18	NP_689899.1	DUF1977	250..350	CDD:286411	44/190 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810