DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10903 and Mettl27

DIOPT Version :9

Sequence 1:	NP_001262365.1	Gene:	CG10903 / 40952	FlyBaseID:	FBgn0037543	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001102969.1	Gene:	Mettl27 / 688407	RGDID:	1588881	Length:	253	Species:	Rattus norvegicus

Alignment Length:	219	Identity:	58/219 - (26%)
Similarity:	87/219 - (39%)	Gaps:	46/219 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FYNDDEAKKYSTNT-----RIIEIQVEMAERALELLALPDDDESRLILDIGCGSGLSGSVLEDSE 73
            || ||.|.:|..:.     |...:.|:...:||:  ..|.|   .||||:.||:||....|:...
  Rat    31 FY-DDWAPEYDQDVAALKYRAPRLAVDCLSQALQ--GPPHD---ALILDVACGTGLVAVELQARG 89

  Fly    74 HMWI-GIDISKSMLDIAVEREVAGDVILGDMG-EGMPFKPGTFDGAISISAL---QWLCNA---- 129
            .:.: |:|.|..||..|..|.:...:.|..:| |.:|:..||||..|.:.||   |..|:|
  Rat    90 FLQVQGVDGSPEMLKQARARGLYHHLSLCTLGQEPLPYPKGTFDAVIIVGALSEGQVPCSAIPEL 154

  Fly   130 ---------------DKSYHNPHKRLLKFFTTLFSCLTRTARAVFQFYPENSDQIEMVTSQ---- 175
                           ....:.|:|..|:  ..|.|  ...|.|..:...:..|..|:.||:
  Rat   155 LRVTKPGGLVCLTTRTNPSNLPYKEALE--AALDS--LEQAGAWERLVTQPVDHWELATSEQESG 215

  Fly   176 ---AMKAGFYGGLVVDYPNSAKAK 196
               ....||..|::..|.....|:
  Rat   216 LATCANDGFISGVIYLYRKQETAQ 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10903	NP_001262365.1	Methyltransf_11	56..142	CDD:285453	30/109 (28%)
CG10903	NP_001262365.1	WBS_methylT	202..272	CDD:289366
Mettl27	NP_001102969.1	Methyltransf_25	71..162	CDD:404528	29/90 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810