DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10903 and mettl27

DIOPT Version :9

Sequence 1:	NP_001262365.1	Gene:	CG10903 / 40952	FlyBaseID:	FBgn0037543	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	XP_021324579.1	Gene:	mettl27 / 678636	ZFINID:	ZDB-GENE-060421-5918	Length:	235	Species:	Danio rerio

Alignment Length:	187	Identity:	38/187 - (20%)
Similarity:	74/187 - (39%)	Gaps:	35/187 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 APPEIFYNDDEAKKYSTNTRIIEIQVEMAERALELLALPDDDESRLILDIGCGSGLSGSVLEDSE 73
            |..::.:.|..|..|..:..:::.:..:...........||.|...:||:.||:||.      |:
Zfish    31 AQDKVGFYDTWADNYEQDVAVLDYRAPLLAAECVSSFFNDDREKATVLDVACGTGLV------SK 89

  Fly    74 HM-------WIGIDISKSMLDIAVEREVAGDVILGDMGEG-MPFKPGTFD-----GAISISALQW 125
            |:       :.|:|.|..||:.|.:..:...::...:|:. :|.|..|:|     ||:|:..:
Zfish    90 HLKRMGFRHFDGVDGSLRMLEGAKKTGLYKQLMHCMLGQDRIPVKAETYDVVIIVGALSVGQV-- 152

  Fly   126 LCNADKSYHNPHKRLLKFFTTL----FSCLTRTARAVFQFYPENSDQIEMVTSQAMK 178
                      |.|.:.:.:...    :.|:|..|....|.|....:|:.....:..|
Zfish   153 ----------PLKVIRELWDATKPGGYVCMTTRANTDNQKYKAELEQMIKALEEEQK 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10903	NP_001262365.1	Methyltransf_11	56..142	CDD:285453	24/98 (24%)
CG10903	NP_001262365.1	WBS_methylT	202..272	CDD:289366
mettl27	XP_021324579.1	Methyltransf_25	77..168	CDD:316196	24/108 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810