DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10903 and SPAC26A3.06

DIOPT Version :9

Sequence 1:	NP_001262365.1	Gene:	CG10903 / 40952	FlyBaseID:	FBgn0037543	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_594149.1	Gene:	SPAC26A3.06 / 2542685	PomBaseID:	SPAC26A3.06	Length:	268	Species:	Schizosaccharomyces pombe

Alignment Length:	282	Identity:	143/282 - (50%)
Similarity:	186/282 - (65%)	Gaps:	25/282 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RPEHSAPPEIFYNDDEAKKYSTNTRIIEIQVEMAERALELLALPDDDESRLILDIGCGSGLSGSV 68
            ||||.|||||||||.||.||||||||..||.||:|||||||   |.:....|||||||||:|..:
pombe     3 RPEHIAPPEIFYNDVEAGKYSTNTRIQSIQTEMSERALELL---DAEGPSFILDIGCGSGISTQI 64

  Fly    69 LEDSEHMWIGIDISKSMLDIAVE-REVAGDVILGDMGEGMPFKPGTFDGAISISALQWLCNADKS 132
            .|...|:.:|:|||.|||.:|:| :|:.||::|.|||.|:||:||||||.|||||:|||.||||:
pombe    65 GESQGHVVVGMDISPSMLSVALESQEIEGDLLLCDMGTGVPFRPGTFDGVISISAIQWLLNADKT 129

  Fly   133 YHNPHKRLLKFFTTLFSCLTRTARAVFQFYPENSDQIEMVTSQAMKAGFYGGLVVDYPNSAKAKK 197
            .:.|.:||.:||.||:..:.|..|||.|:|||.....:|:...|.||||.||:|||:|.|.:.||
pombe   130 CNVPQRRLNRFFQTLYISMKRGGRAVMQYYPETEKSQQMIMDTARKAGFAGGIVVDHPESKRQKK 194

  Fly   198 YYLVLMTGG-------SAELPQALGSPEEERRVNYIKKRDACREARGKAPKKSRDWILAKKERRR 255
            |||||..||       |..|.|. |:..::|::.  ||:|          ..:|::|:.|||..|
pombe   195 YYLVLQAGGTRTLDISSMTLDQE-GTNAKQRKLK--KKQD----------MSTREYIIHKKELNR 246

  Fly   256 RQG-LETRPDTKYTARKRSGKF 276
            ::| |....|:||:.|:|...|
pombe   247 KRGRLHVPKDSKYSGRRRKAAF 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10903	NP_001262365.1	Methyltransf_11	56..142	CDD:285453	51/86 (59%)
CG10903	NP_001262365.1	WBS_methylT	202..272	CDD:289366	23/77 (30%)
SPAC26A3.06	NP_594149.1	AdoMet_MTases	51..159	CDD:100107	61/107 (57%)
SPAC26A3.06	NP_594149.1	WBS_methylT	<221..266	CDD:289366	17/56 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	101	1.000	Domainoid score	I1804
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5486
Inparanoid	1	1.050	257	1.000	Inparanoid score	I757
OMA	1	1.010	-	-		QHG53740
OrthoFinder	1	1.000	-	-		FOG0004742
OrthoInspector	1	1.000	-	-		oto101784
orthoMCL	1	0.900	-	-		OOG6_102190
Panther	1	1.100	-	-	LDO	PTHR12734
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1706
SonicParanoid	1	1.000	-	-		X3338
TreeFam	1	0.960	-	-
	14	13.860