DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10903 and C27F2.4

DIOPT Version :9

Sequence 1:	NP_001262365.1	Gene:	CG10903 / 40952	FlyBaseID:	FBgn0037543	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_498051.1	Gene:	C27F2.4 / 175671	WormBaseID:	WBGene00016166	Length:	283	Species:	Caenorhabditis elegans

Alignment Length:	278	Identity:	151/278 - (54%)
Similarity:	203/278 - (73%)	Gaps:	6/278 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RPEHSAPPEIFYNDDEAKKYSTNTRIIEIQVEMAERALELLALPDDDESRLILDIGCGSGLSGSV 68
            :|||:.||:::||:.||.||::|:.|..||.||||||||||||| :.:|..:||||||:|:|..|
Worm     7 KPEHTGPPDLYYNETEAAKYASNSHITAIQHEMAERALELLALP-EGKSGFLLDIGCGTGMSSEV 70

  Fly    69 LEDSEHMWIGIDISKSMLDIAVERE--VAGDVILGDMGEGMPFKPGTFDGAISISALQWLCNADK 131
            :.|:.||::|:|:|:.||:||.:.|  .:||.|..|||.||||:||:|||||||||:||||:|:.
Worm    71 ILDAGHMFVGVDVSRPMLEIARQDEDLESGDFIHQDMGLGMPFRPGSFDGAISISAIQWLCHANA 135

  Fly   132 SYHNPHKRLLKFFTTLFSCLTRTARAVFQFYPENSDQIEMVTSQAMKAGFYGGLVVDYPNSAKAK 196
            |..||.||||.||.:|:.||.|.:||||||||||.:|.:::..||.||||.||||||:|.:||.|
Worm   136 SDENPRKRLLFFFQSLYGCLGRGSRAVFQFYPENDEQCDLIMGQAHKAGFNGGLVVDFPEAAKRK 200

  Fly   197 KYYLVLMTGGSAELPQALGSPEEERR--VNYIKKRDACREARG-KAPKKSRDWILAKKERRRRQG 258
            |.||||||||..:|||||....||.|  ::...:|......:. |..|.|:.||.||::|:.:||
Worm   201 KVYLVLMTGGVVQLPQALTEDGEESRTQIDNAGRRFVWNSRKNEKVAKGSKAWIEAKRQRQIKQG 265

  Fly   259 LETRPDTKYTARKRSGKF 276
            .:.|.::||:.|||..||
Worm   266 RDVRHESKYSGRKRKTKF 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10903	NP_001262365.1	Methyltransf_11	56..142	CDD:285453	52/87 (60%)
CG10903	NP_001262365.1	WBS_methylT	202..272	CDD:289366	28/72 (39%)
C27F2.4	NP_498051.1	SmtA	23..253	CDD:223574	128/230 (56%)
		Methyltransf_11	58..163	CDD:285453	61/104 (59%)
		WBS_methylT	206..281	CDD:289366	30/74 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163599
Domainoid	1	1.000	99	1.000	Domainoid score	I4481
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5486
Inparanoid	1	1.050	295	1.000	Inparanoid score	I1671
Isobase	1	0.950	-	0	Normalized mean entropy	S550
OMA	1	1.010	-	-		QHG53740
OrthoDB	1	1.010	-	-		D1138059at2759
OrthoFinder	1	1.000	-	-		FOG0004742
OrthoInspector	1	1.000	-	-		oto17644
orthoMCL	1	0.900	-	-		OOG6_102190
Panther	1	1.100	-	-	LDO	PTHR12734
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1706
SonicParanoid	1	1.000	-	-		X3338
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750