DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pbp95 and Ttf1

DIOPT Version :9

Sequence 1:	NP_649760.1	Gene:	Pbp95 / 40949	FlyBaseID:	FBgn0037540	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	XP_006233944.1	Gene:	Ttf1 / 499766	RGDID:	1565673	Length:	912	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	77/465 - (16%)
Similarity:	155/465 - (33%)	Gaps:	142/465 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 KRKPIERHLSTLVSL--LATADSSFSID-WNQISTL--DLEYRHSPYSCEAMWRVYLTPDLRRDD 231
            :.|.||:::...:||  :.:||.....| :.:..:|  :|:.:|:       :|:::...:.|.
  Rat   542 ENKQIEKNVQDFLSLTGIESADKLLYTDRYPEEKSLITNLKRKHA-------FRLHIGKGIARP- 598

  Fly   232 WSPEEDETLLAVATANRMQNWELIAASLDRRSDYQCFVRFHTALRFLLEPKNSHRWSEEDNDKLR 296
                                |:|:               ::.|.:.........|::|||..||:
  Rat   599 --------------------WKLV---------------YYRAKKIFDVNNYKGRYNEEDTKKLK 628

  Fly   297 AIVDRNTANSVINWKKVVEYFPDKSKSTLIGRYYYVLHPSISHEPFTTKEDMMLFAAVEEYNGKF 361
            |....: .|   :|||:.......|.|  :...:..:....:|..::..|...|..|||:.
  Rat   629 AYHSLH-GN---DWKKIGAMVARSSLS--VALKFSQIDGDRNHGTWSKAETQRLIKAVEDV---- 683

  Fly   362 HCFPRSLFPNRSLTQLRTRYHNVLAQRNKTDSWSVQDDTRLMSFVTQ--YGASQWLNCATFLGNH 424
                  :....|..:||           :.||...:|....:|.|.:  |....|:.....:...
  Rat   684 ------ILKKMSSQELR-----------ELDSRLQEDPEGRLSIVREKLYKGISWVEVEARVETR 731

  Fly   425 TRTSCRTRF--LVIKKFLE--------QNPNAKVEDLPRRRSKKVSLVNSDNWAQRLQEWQEDPE 479
            ....|::::  ::.|:...        :...||:..:.|.....|:..|..:|        ||..
  Rat   732 NWMQCKSKWTEILTKRMTHGGFVYRGVKALQAKITLIERLYELNVNDANEIDW--------EDLA 788

  Fly   480 SLVNDNPPKGTRVRGPKSKKARIE-RQAESFSRLSKVDIEFCNFFKFSYNLTLSTPKTFPVPKDV 543
            ..:.|.||...:.:..|.|.|.:. .|.::|..:..:             :....|.|.....|:
  Rat   789 GAIGDVPPPFVQAKFYKLKAACVPFWQKKTFPGVGII-------------IKALRPLTLEAYTDM 840

  Fly   544 YNLAYVIRALAY------------------------KPPIRPSLLQNIFMPNDVLKCYNSMIRNL 584
            ..:.:.:..:.|                        :.|..|.  || |:..|:..|.:.
  Rat   841 SKMTFSVEIIDYLYENSLPLLKEKLAKKMKKKDSQIQKPTAPK--QN-FLFKDIFHCDDD----- 897

  Fly   585 PDEEGDMKSP 594
             .:||.::.|
  Rat   898 -SDEGGLEEP 906

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pbp95	NP_649760.1	DUF883	4..>74	CDD:295076
		SANT	<194..240	CDD:304392	6/48 (13%)
		SANT	229..276	CDD:197842	4/46 (9%)
		Myb_DNA-binding	229..275	CDD:278669	3/45 (7%)
		Myb_DNA-bind_6	287..350	CDD:290632	14/62 (23%)
		SANT	392..438	CDD:197842	8/49 (16%)
		Myb_DNA-binding	393..437	CDD:278669	7/47 (15%)
Ttf1	XP_006233944.1	Myb_DNA-bind_6	621..676	CDD:290632	14/60 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900