DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pbp95 and ttf1.6

DIOPT Version :9

Sequence 1:	NP_649760.1	Gene:	Pbp95 / 40949	FlyBaseID:	FBgn0037540	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	XP_005168698.1	Gene:	ttf1.6 / 449954	ZFINID:	ZDB-GENE-041008-214	Length:	549	Species:	Danio rerio

Alignment Length:	387	Identity:	74/387 - (19%)
Similarity:	127/387 - (32%)	Gaps:	141/387 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   337 ISHEPFTTKEDMML------FAAVEEYNGKFHCFPRSLFPNRS--LTQLRTRY------------ 381
            :.|..|:|.|:..|      |.|:.........|....||..|  |..|:.:|
Zfish   210 LRHGRFSTAENERLRQNVSNFLALTGVKDAIKLFHPKRFPKESQTLANLKRKYSFFVKIAEGIPR 274

  Fly   382 --HNVLAQ-------RNKTDSWSVQDDTRLMSFVTQYG-----------------ASQWLNCATF 420
              |:|..:       |||..:::.:::..|:.:.|.||                 ..::.:.:..
Zfish   275 PCHDVYTRGTKIYDDRNKKGNFTEEEEKSLLKYYTLYGPDWKKISDKTDRSSYSLEKRFSHLSKI 339

  Fly   421 LGNHTRTSCR-----TRFLVIKKFLEQNPNAKVEDLPRRRSKKV-----------SLVNSDNWAQ 469
            .|..|....:     .|..|:......||..|   .|:|.|:::           ..|.:..|.:
Zfish   340 RGPWTTNEVQRLLRAVRDHVVSVLKSANPKKK---KPKRVSREILYQALPWSKIAEKVKTRCWTK 401

  Fly   470 RLQEWQEDPESLVNDNPPKGTRVRGPKSKKARI-------ERQAESFSRLSKVDIEFCNFFKFSY 527
            ...:|.    |::......|...||.|:::|:|       |.|.|..     ||:::       .
Zfish   402 CRDKWM----SILASRMSSGITFRGRKAQEAKIKLIRAMYEMQVEDV-----VDVDW-------E 450

  Fly   528 NLTLSTPKTFPVPKDVYNLAYVIRALAYKPPI----RPSLLQNIFMPNDVLKCYNSMI------- 581
            :||       .|..||             ||.    |...|:..::|:...||:..::
Zfish   451 HLT-------AVFGDV-------------PPAYAQSRWHQLKVCYVPDWQNKCFGDIVDFLYENT 495

  Fly   582 --------RNLPDEEGDMKSPLLPPNWSTMMGFRALCI---LSGD--CRKDTETRSFEYNES 630
                    ::|.|:|..:         ..|..||...|   ::.|  |..|.:|...|.|.|
Zfish   496 LPGLVKECKDLDDDELTV---------DQMNSFRLADIFQDINEDECCDDDEQTGQQENNHS 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pbp95	NP_649760.1	DUF883	4..>74	CDD:295076
		SANT	<194..240	CDD:304392
		SANT	229..276	CDD:197842
		Myb_DNA-binding	229..275	CDD:278669
		Myb_DNA-bind_6	287..350	CDD:290632	4/12 (33%)
		SANT	392..438	CDD:197842	8/67 (12%)
		Myb_DNA-binding	393..437	CDD:278669	8/65 (12%)
ttf1.6	XP_005168698.1	Myb_DNA-bind_6	296..351	CDD:290632	6/54 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900