Protein Alignment CG10435 and UBAP1

DIOPT Version :10

• Sequence 1: NP_649759.1
• Gene: CG10435 / 40948
• FlyBaseID: FBgn0037539
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_001164672.1
• Gene: UBAP1 / 51271
• HGNCID: 12461
• Length: 566
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 115/549 - (20%)
• Similarity: 199/549 - (36%)
• Gaps: 160/549 - (29%)

  Fly     1 MEDVPVKIVERYKPP-----PAVYHLPQATLNRLSQFREGFYTDHPDYQYDCQLERAVLSQAQRW 60
            ::|||.|..:::|.|     |..:.||..    |...||        .|||..||:..:..|:..
Human    81 LDDVPFKTGDKFKTPAKVGLPIGFSLPDC----LQVVRE--------VQYDFSLEKKTIEWAEEI 133

  Fly    61 RHLRRQQREERASRQERRKEERQRALEARQKEMLGAVDYPSADDLSSDEDEKERKKNEPE----- 120
            :.:...:||                                |:...::.:.|...|:.||
Human   134 KKIEEAERE--------------------------------AECKIAEAEAKVNSKSGPEGDSKM 166

  Fly   121 --QRDEEQQQQPPP--PITAESRDSSHEPKSISVCNFHNILQPTILSTT----PVVSPQTLHKRN 177
              .:.......|||  ||.|..:.:|             ||.||.:|::    .|:||..:   .
Human   167 SFSKTHSTATMPPPINPILASLQHNS-------------ILTPTRVSSSATKQKVLSPPHI---K 215

  Fly   178 SSLNYADFEYNMNSTPFDNIELKTINDLD------------ILAQVLHQT----------QLEKR 220
            :..|.||||  ....||||:|||||::.:            |:||:|...          |.|:.
Human   216 ADFNLADFE--CEEDPFDNLELKTIDEKEELRNILVGTTGPIMAQLLDNNLPRGGSGSVLQDEEV 278

  Fly   221 IDQQQQDQQQQEPPHEDHS--KEEQSGN--------EV---PAPVELAMTTLAETKATLDSVNFH 272
            :...::.....:|.|:.:.  ...|.||        :|   |.|....:.:|:..|  |||
Human   279 LASLERATLDFKPLHKPNGFITLPQLGNCEKMSLSSKVSLPPIPAVSNIKSLSFPK--LDS---- 337

  Fly   273 VHCDDNADRGEPSHIPTTAQYLTPMYSASAQQPLHKPEHFQVYHMQGYSHQPFYPPQQHSFQQFS 337
               ||:..:        ||:..:..:|.|..:             .|.......|..|.|..:.:
Human   338 ---DDSNQK--------TAKLASTFHSTSCLR-------------NGTFQNSLKPSTQSSASELN 378

  Fly   338 NYQVNGFGTQNLLKAP--PAPSSVHALSQSEDEVATKSRSVPDILRELKTELQQAEKRRTRLHSH 400
            .:...|....||....  ||.:|....|.|...|.|:..|.|:....:...            :.
Human   379 GHHTLGLSALNLDSGTEMPALTSSQMPSLSVLSVCTEESSPPNTGPTVTPP------------NF 431

  Fly   401 NAEQQPTVELAVDRNSFRELAGPAQK-LAQRISTMGFPLERVAKVVSLCGIDDKKIIEHLIPLGE 464
            :..|.|.:.......|..::..|::: ..:.:..||:..|.|.:.:...|.:.::|:::|...|:
Human   432 SVSQVPNMPSCPQAYSELQMLSPSERQCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAHGQ 496

  Fly   465 LLDLGFDESKISAALLKFNNNKDKALDYL 493
            |.:.|||...:..||.....:::|.:::|
Human   497 LCEKGFDPLLVEEALEMHQCSEEKMMEFL 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10435	NP_649759.1	UBA2_UBAP1_like	458..494	CDD:270501	10/36 (28%)
UBAP1	NP_001164672.1	UBA1_UBAP1	452..494	CDD:270500	8/41 (20%)
		UBA2_UBAP1_like	524..560	CDD:270501	1/2 (50%)