Protein Alignment CG2767 and AKR1C3

DIOPT Version :10

• Sequence 1: NP_649757.1
• Gene: CG2767 / 40946
• FlyBaseID: FBgn0037537
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_003730.4
• Gene: AKR1C3 / 8644
• HGNCID: 386
• Length: 323
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 119/323 - (36%)
• Similarity: 192/323 - (59%)
• Gaps: 15/323 - (4%)

  Fly    10 NNGEKMPVIGIGTWQASDEEIETAIDA---ALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKVK 71
            |:|..|||:|.||:...:.....|::.   |:|||:||||:|.:|.||:.:|..::..:..|.||
Human    11 NDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75

  Fly    72 REELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKEGLMEV 136
            ||::|..:|:....:||..|.|.::.||:..|||||||||:|:|.::...|:.| ..|:.|.:..
Human    76 REDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELS-PTDENGKVIF 139

  Fly   137 DVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLK--NCKIRPANNQIEHHVYLQQRDLV 199
            |: .:....|.|||...:.||.||||||||::.|:..:|.  ..|.:|..||:|.|.|..:..|:
Human   140 DI-VDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 203

  Fly   200 DFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIIDT 264
            |||||::|.:.|||.|||:...::     :..:.|.|::.|.:..:|..|.:|||.:.||:.:..
Human   204 DFCKSKDIVLVAYSALGSQRDKRW-----VDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263

  Fly   265 GVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHPEFTFKNQY 327
            ||..:.||.|..|::||:.||:|:||||::..:..||:|:...:...|   ..||.:.:.::|
Human   264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSF---ASHPNYPYSDEY 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2767	NP_649757.1	AKR_AKR1I_CgAKR1	4..309	CDD:381381	115/303 (38%)
AKR1C3	NP_003730.4	AKR_AKR1C1-35	6..306	CDD:381334	115/301 (38%)