Protein Alignment CG2767 and AKR1B10

DIOPT Version :10

• Sequence 1: NP_649757.1
• Gene: CG2767 / 40946
• FlyBaseID: FBgn0037537
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_064695.3
• Gene: AKR1B10 / 57016
• HGNCID: 382
• Length: 316
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 138/327 - (42%)
• Similarity: 199/327 - (60%)
• Gaps: 19/327 - (5%)

  Fly     6 FLTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKV 70
            |:..:...|||::|:|||::...:::.|:..|::|||||||.|.||.||..:|..::..:....|
Human     4 FVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAV 68

  Fly    71 KREELFIVTKV-PPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKEGLM 134
            |||:||||:|: |....|| .|....:|:|:||:|.|:|:||:|.|......:|...|.||...:
Human    69 KREDLFIVSKLWPTFFERP-LVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAI 132

  Fly   135 EVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLK--NCKIRPANNQIEHHVYLQQRD 197
            ....|...|  |.|||.||::||.|::||||||..|:.:||.  ..|.:|..||:|.|.||.|..
Human   133 GGKATFLDA--WEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK 195

  Fly   198 LVDFCKSENITVTAYSPLGS--KGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRW 260
            |:.:|.|:.|||||||||||  :..||        .:.|.|::.|::|||||.|.||.||||:|:
Human   196 LIQYCHSKGITVTAYSPLGSPDRPWAK--------PEDPSLLEDPKIKEIAAKHKKTAAQVLIRF 252

  Fly   261 IIDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHPEFTFKN 325
            .|...|..||||..|||:.:|:.||||:|:.||:|.:.|.::|.|.|:......:|.:|   |..
Human   253 HIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLEDYP---FNA 314

  Fly   326 QY 327
            :|
Human   315 EY 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2767	NP_649757.1	AKR_AKR1I_CgAKR1	4..309	CDD:381381	134/307 (44%)
AKR1B10	NP_064695.3	AKR_AKR1B1-19	10..316	CDD:381333	136/319 (43%)