DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2767 and akr1a1

DIOPT Version :9

Sequence 1:	NP_649757.1	Gene:	CG2767 / 40946	FlyBaseID:	FBgn0037537	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_001016137.1	Gene:	akr1a1 / 548891	XenbaseID:	XB-GENE-1014353	Length:	327	Species:	Xenopus tropicalis

Alignment Length:	340	Identity:	128/340 - (37%)
Similarity:	201/340 - (59%)	Gaps:	35/340 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KFLTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGK 69
            ::.|...|:|:|:||:|||:::..:::.|:..||..||||||.|.|||||..:|..:|..:.:.|
Frog     6 EYETLYTGQKIPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGSDK 70

  Fly    70 -VKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKEGL 133
             :.|||:|:.:|:....:.|.:||..::|:|:||||||:||||:|.|:... ..|..|..:.:|.
Frog    71 GLSREEVFVTSKLWNNKHHPDDVECALRKTLQDLQLDYLDLYLMHWPYAFK-RGDQIFPQNPDGS 134

  Fly   134 MEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQRDL 198
            ::.|: |::...|.|||.||::||||:||:|||:|.|:..::....::||..|:|.|.||.|.:|
Frog   135 VQYDL-TDYKDTWKAMEKLVKQGLTKAIGLSNFNKRQIDDIISIATVKPAVLQVECHPYLAQNEL 198

  Fly   199 VDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPD----------LMDIPEVKEIAASHGKTP 253
            :.:|.:..:..|.||||||                ||          |::.|.:..:|..:||:.
Frog   199 IAYCHAHGLVFTGYSPLGS----------------PDRSWRKPEDPVLLEEPGIIAMAKKYGKSE 247

  Fly   254 AQVLLRWIIDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIR-ICDFAFFHG--V 315
            ||:||||.:...|.:||||..|.|:.||..||||.|:.||:..:.:|::|.| |......:|  |
Frog   248 AQILLRWQVQRKVVSIPKSVTPTRILQNFQVFDFSLSEEEMQLIGALNKNWRYIIPLITVNGKSV 312

  Fly   316 ER---HPEFTFKNQY 327
            .|   ||.:.|.:.|
Frog   313 PRDAGHPLYPFNDPY 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2767	NP_649757.1	ARA1	5..302	CDD:223729	118/307 (38%)
CG2767	NP_649757.1	Tas	10..297	CDD:223739	116/297 (39%)
akr1a1	NP_001016137.1	AKR_AKR1A1-4	10..314	CDD:381332	122/321 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930