Protein Alignment CG2767 and Akr1b8

DIOPT Version :10

• Sequence 1: NP_649757.1
• Gene: CG2767 / 40946
• FlyBaseID: FBgn0037537
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_032038.1
• Gene: Akr1b8 / 14187
• MGIID: 107673
• Length: 316
• Species: Mus musculus
• Alignment Length: 318
• Identity: 131/318 - (41%)
• Similarity: 197/318 - (61%)
• Gaps: 14/318 - (4%)

  Fly     6 FLTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKV 70
            |:..:...|||::|:|||::...:::.|:.||::|||||||.|..|.||..:|..::..:....|
Mouse     4 FVELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAV 68

  Fly    71 KREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKEGLME 135
            :||:||||:|:.|.......::...:|:|.||:|||:||||:|.|..:...:: .|..|.:|.:.
Mouse    69 QREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE-LFPKDDQGRIL 132

  Fly   136 VDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLK--NCKIRPANNQIEHHVYLQQRDL 198
            ...||...| |..||.||::||.|::|||||:..|:.|||.  ..|.:|..||:|.|.||.|..|
Mouse   133 TSKTTFLEA-WEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKL 196

  Fly   199 VDFCKSENITVTAYSPLGS--KGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWI 261
            :.:|.|:.|:|||||||||  :..||        .:.|.|::.|::|||||.|.||.||||:|:.
Mouse   197 IQYCHSKGISVTAYSPLGSPDRPSAK--------PEDPSLLEDPKIKEIAAKHEKTSAQVLIRFH 253

  Fly   262 IDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHP 319
            |...|..||||..|:|:::|:.||||:|:.||:|.:.|.::|.|.|.......:|.:|
Mouse   254 IQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMATILSFNRNWRACLLPETVNMEEYP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2767	NP_649757.1	AKR_AKR1I_CgAKR1	4..309	CDD:381381	129/306 (42%)
Akr1b8	NP_032038.1	AKR_AKR1B1-19	10..316	CDD:381333	130/312 (42%)