Protein Alignment CG2767 and AKR1A1

DIOPT Version :9

• Sequence 1: NP_649757.1
• Gene: CG2767 / 40946
• FlyBaseID: FBgn0037537
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_001189342.1
• Gene: AKR1A1 / 10327
• HGNCID: 380
• Length: 325
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 135/325 - (41%)
• Similarity: 201/325 - (61%)
• Gaps: 15/325 - (4%)

  Fly    10 NNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGK-VKRE 73
            :.|:|||:||:|||::...:::.|:..||..||||||.|.:||||..||..||..:..|| |.||
Human     9 HTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPRE 73

  Fly    74 ELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKEGLMEVDV 138
            |||:.:|:....:.|.:|||.::|:|.||||:|:||||:|.|:... ..|..|..:.:|.:..|
Human    74 ELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE-RGDNPFPKNADGTICYD- 136

  Fly   139 TTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQRDLVDFCK 203
            :|::...|.|:||||.|||.:::|:|||:..|:..:|....:|||..|:|.|.||.|.:|:..|:
Human   137 STHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQ 201

  Fly   204 SENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIIDTGVSA 268
            :..:.|||||||||...|..:.      |.|.|::.|.|..:|..:|::|||:||||.:...|..
Human   202 ARGLEVTAYSPLGSSDRAWRDP------DEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVIC 260

  Fly   269 IPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIR-ICDFAFFHG--VER---HPEFTFKNQY 327
            ||||..|:|:.||:.||||..:.||:.:|::|::|.| |.......|  |.|   ||.:.|.:.|
Human   261 IPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY 325

  Fly   328  327
            Human   326  325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2767	NP_649757.1	ARA1	5..302	CDD:223729	125/292 (43%)
		Tas	10..297	CDD:223739	123/287 (43%)
AKR1A1	NP_001189342.1	ARA1	6..303	CDD:223729	128/301 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830