Protein Alignment CG2698 and Tmem245

DIOPT Version :10

• Sequence 1: NP_001246976.1
• Gene: CG2698 / 40945
• FlyBaseID: FBgn0037536
• Length: 869
• Species: Drosophila melanogaster
• Sequence 2: XP_006238250.1
• Gene: Tmem245 / 298020
• RGDID: 1308958
• Length: 888
• Species: Rattus norvegicus
• Alignment Length: 936
• Identity: 255/936 - (27%)
• Similarity: 413/936 - (44%)
• Gaps: 184/936 - (19%)

  Fly     3 RSEPIPIRRDRSFDSVINRLLRMRSQNHESFRAAMYNFLIAAGVAAFVAVC--------FILGPF 59
            ||||...|.....::.....|.:|..  :..:.|.||    .|...||.:|        |||..|
  Rat    18 RSEPRVPRTAGPSETPRTAALALRFD--KPIKQAFYN----TGAVLFVCLCCGAAVLVYFILEAF 76

  Fly    60 VRPLLWAFLMGAVLFPFKRRLAESVNSWFHRLEVRDSNVLVSICLSPLEATEH------------ 112
            :||||||.|.|..|.|||..|......|..||....:.::::..|.||...::
  Rat    77 LRPLLWAVLCGTFLHPFKSSLTRLGRLWLRRLHRAHTPIVLAALLLPLCFADYGVEALGEQALRR 141

  Fly   113 ---------CGRLLIGWLC----EHWQLLLAGCGVAGCIKLLVLYAPKGFLLAIWHWITFSHGLF 164
                     .|.||.|..|    ...|:|||..|...|..|       .:..::|.|
  Rat   142 RRLLLLLGAGGPLLYGLYCLGSYLGVQVLLAHAGALICRGL-------DYFSSLWIW-------- 191

  Fly   165 VQIIGFLNVYVLISLIVVYLSCVHFFWRPENSAHFVVAGQSMWIAVAGYLSSFLGALQVPVFLLV 229
                         :|:|.|:..|.|.|......:.......:|:.:..:::|..|:.::||||::
  Rat   192 -------------TLVVGYVLMVSFKWNASTQHYLRAVSIPVWMILLFHIASLAGSWRIPVFLVI 243

  Fly   230 MTYVTASTAYHLQTLDDS------GSYLHRLQKLFDKNDFERSLSNFSICGRPGNEPLSPGLQSD 288
            :..::|.|.|..|...:|      |..:.....         :|:|.:|.        ..|.:|.
  Rat   244 VFLMSAGTLYEKQNEKESAGAELPGQVISMAAS---------TLANLAIS--------ITGYESS 291

  Fly   289 VEDVSLSDTVDSTDTFDVKPETEVPSHQ-----------------------------SDTFFKLL 324
            .||.....:.:.||..:..|.....|..                             ||.:|..|
  Rat   292 SEDQPSDPSAEPTDKGEPPPAPSASSSSSSRSSPSSPSPTLGRQRPEMGTFLRKKKTSDIYFVSL 356

  Fly   325 FYACLGTFLYRNVWMFILAAIPVILHLIYTVGEYTGITKFVCNKISEVYAALRFWAIEHHSAVLP 389
            .:|.:...|:.|:|:..|..:||.:.:|..:..:.|:..|:..:....:..:..:..|...|:.|
  Rat   357 VWAIIAVQLWLNLWIVQLLPVPVAVWIIKKLVIHFGVVGFLEKRCRAWWQVMESFLKERQEALAP 421

  Fly   390 LCLPG----VLELNYK----INTIVRDSLKASVESVTSILMIILMLLIIVFLSVFFCVNIYSETI 446
            ..:.|    :|:::.|    :|..:...|:..::.:.||.:|.|:::..:.|::.....::.|::
  Rat   422 WPITGLGKFLLKVDSKLWHWLNKKMIIWLEKMLDKIISIFIIFLLVIGTLLLALLLTAKVHQESV 486

  Fly   447 EVAYLGKDLINKTITDRPELIDILPAN--MQSSIEDALDNAHHYGRRKIETYIDDWLAD------ 503
            .:..:...|||:|:.:.||..:.||..  :|.::..|.:|.:.|||        :|:..
  Rat   487 HMIEVTSSLINETLANHPEWANWLPEAQVVQRALNSAANNVYQYGR--------EWITHKLHKIL 543

  Fly   504 ADKVHATK-LKEQILEVWDRLIQYWI--DFNKAGSSYGPRVPTDALKSTFGEIVDNPELVLVAKQ 565
            .|||:.|. :::|:||:||||...|.  :...:|...|.::......|..|:|:|        .|
  Rat   544 GDKVNNTAVIEKQVLELWDRLYHSWFVKNVTHSGRHKGHKMHVSRQNSWLGDILD--------WQ 600

  Fly   566 GIIGWAQSNTQTIL------------EVAESLWHIIRTNMSMIMGVTGEILSLVLSGGQACIEFI 618
            .|..:...|.:|.|            ::.||||.::..|:|::......:|:::...|.|.:.|:
  Rat   601 DIASFVHENIETFLSILSFGFQIWKMKILESLWIVMSRNVSLLFTTVTTLLTILFYSGTALLNFV 665

  Fly   619 LDMIVFFTALFYLLSSSQEKYAP----LQITKYLGYSSSGIKIADALENSITVVLVSMFRCSTFT 679
            |.:|:|.|.||||||||.|.|.|    :.:|.......|...|..::|.:|..|..:..:.:.|.
  Rat   666 LSLIIFLTTLFYLLSSSDEYYKPVKWVISLTPLSQPGPSSNIIGQSVEEAIRGVFDASLKMAGFY 730

  Fly   680 GLFTWLVHTVFGARIVFLPSALAAMLAAAPFLGSYWCAVPAFLELWLAQDRFYAGL----ILFLL 740
            ||:|||.|||||..|||:||||||:|.|.||||:||.||||.|:|||.|     ||    :|.|:
  Rat   731 GLYTWLTHTVFGINIVFIPSALAAILGAVPFLGTYWAAVPAVLDLWLTQ-----GLGCKAVLLLV 790

  Fly   741 QFFVPSSF-ETAIYADLK-GGHPYLNGLAIAGGMYWIGWQGAIFGPLMLCFFIGLFEVATLAMRS 803
            ...:|:.| :||||:|:. ||||||.|||:|||.|::|.:|||.||::||..:....:.:..:.|
  Rat   791 FHLLPTYFVDTAIYSDISGGGHPYLTGLAVAGGAYYLGLEGAIIGPILLCILVVASNIYSAMLVS 855

  Fly   804 HQEPRNSTDEERTTSIPRRVNETVND 829
               |.||......|..|.:...|..|
  Rat   856 ---PTNSMPTPSQTPWPAQTQRTFRD 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2698	NP_001246976.1	PerM	<565..795	CDD:440393	105/251 (42%)
Tmem245	XP_006238250.1	PerM	<608..849	CDD:440393	103/245 (42%)